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100202 N,N-Dimethylformamide

100202
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar Mass
68-12-2200-679-5C₃H₇NOHCON(CH₃)₂73.09 g/mol

Products

Catalogue NumberPackaging Qty/Pack
1.00202.1000 Glass bottle 1 l
1.00202.2500 Glass bottle 2.5 l
Description
Catalogue Number100202
SynonymsDMF, N,N-Dimethylmethanamide, Formic acid dimethylamide
DescriptionN,N-Dimethylformamide
OverviewSupraSolv® solvents for headspace gas chromatography are developed particularly for the analysis of residual solvents in drug substances, excipients and drug products according to ICH, Ph Eur and USP - SupraSolv® headspace solvents are tested for all residual solvents defined by the ICH.
References
Product Information
CAS number68-12-2
EC index number616-001-00-X
EC number200-679-5
Hill FormulaC₃H₇NO
Chemical formulaHCON(CH₃)₂
Molar Mass73.09 g/mol
HS Code2924 19 00
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
ApplicationN,N-Dimethylformamide for headspace gas chromatography SupraSolv®. CAS 68-12-2, EC Number 200-679-5, chemical formula HCON(CH₃)₂.
Biological Information
Physicochemical Information
Boiling point153 °C (1013 hPa)
Density0.944 g/cm3 (25 °C)
Explosion limit2.2 - 16 %(V)
Flash point57.5 °C
Ignition temperature410 °C
Melting Point-61 °C (External MSDS)
pH value7 (200 g/l, H₂O, 20 °C)
Vapor pressure3.77 hPa (20 °C)
Solubility1000 g/l soluble
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat 3010 mg/kg
LD 50 dermalLD50 Rabbit 1500 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Statement(s)H226: Flammable liquid and vapour.
H312 + H332: Harmful in contact with skin or if inhaled.
H319: Causes serious eye irritation.
H360D: May damage the unborn child.
Precautionary Statement(s)P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
P303 + P361 + P353: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.
P304 + P340 + P312: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
Signal WordDanger
RTECSLQ2100000
Storage class3 Flammable liquids
WGKWGK 2 obviously hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Categories of dangertoxic for reproduction, harmful, irritant
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +30°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDUN 2265 , 3, III
Declaration (transport by air) IATA-DGRUN 2265 , 3, III
Declaration (transport by sea) IMDG-CodeUN 2265 , 3, III
Supplemental Information
Specifications
Purity (GC)≥ 99.8 %
Identity (IR)conforms
Evaporation residue≤ 3.0 mg/l
Water≤ 0.05 %
Color≤ 10 Hazen
GC/HS (Every residual solvent of class 1 acc. ICH)≤ 1 µg/g
GC/HS (Every residual solvent of class 2 acc. ICH)≤ 10 µg/g
GC/HS (Every residual solvent of class 3 acc. ICH)≤ 50 µg/g
Suitable as solvent for the analysis of residual solvents of ICH classes 1,2 and 3 according to Ph Eur und USP.
Formic acid and acetic acid are not detected.
Global Trade Item Number
Catalogue Number GTIN
1.00202.1000 04027269198053
1.00202.2500 04027269198060

Related Products & Applications

Accessories (Secondary)

Catalogue Number Description
100801 Label set acc. GHS
108801 Bottle key
963533 Safety carrier

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Categories

Analytics and Sample Preparation > Analytical Chromatography > Gas Chromatography GC > Solvents for Headspace Gas Chromatography, SupraSolv®
Reagents, Chemicals and Labware > Solvents > Solvents for Instrumental Organic Analysis > Solvents for Headspace Gas Chromatography, SupraSolv®