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106756 Methyl 4-hydroxybenzoate sodium salt

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
5026-62-0225-714-1C₈H₇NaO₃Na⁺[4-(O)C₆H₄(COOCH₃)]⁻174.13 g/molPh Eur,BP,NF

Products

Catalogue NumberPackaging Qty/Pack
1.06756.5000 Plastic bottle 5 kg
Description
Catalogue Number106756
Synonyms4-Hydroxybenzoic acid methyl ester sodium salt, Methylparaben sodium salt
DescriptionMethyl 4-hydroxybenzoate sodium salt
References
Product Information
CAS number5026-62-0
EC number225-714-1
GradePh Eur,BP,NF
Hill FormulaC₈H₇NaO₃
Chemical formulaNa⁺[4-(O)C₆H₄(COOCH₃)]⁻
Molar Mass174.13 g/mol
HS Code2918 29 22
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Density1.42 g/cm3 (20 °C)
Ignition temperature>600 °C
Melting Point>125 °C
pH value9.7 - 10.3 (1 g/l, H₂O)
Bulk density700 kg/m3
Solubility333 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat > 5000 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Statement(s)H315: Causes skin irritation.
H318: Causes serious eye damage.
H412: Harmful to aquatic life with long lasting effects.
Precautionary Statement(s)P264: Wash skin thoroughly after handling.
P273: Avoid release to the environment.
P280: Wear protective gloves/ eye protection/ face protection.
P302 + P352: IF ON SKIN: Wash with plenty of water.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
Signal WordDanger
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Categories of dangerirritant
Product Usage Statements
Storage and Shipping Information
StorageStore at +15°C to +25°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDKein Gefahrgut
Declaration (transport by air) IATA-DGRNo Dangerous Good
Declaration (transport by sea) IMDG-CodeNo Dangerous Good
Supplemental Information
Specifications
Assay (HPLC, calc. on anhydrous substance, Ph.Eur.)95.0 - 102.0 %
Assay (HPLC, calc. on anhydrous substance, NF)95.0 - 102.0 %
Identity (IR-spectrum)passes test
Identity (wet chemistry)passes test
Appearance of solution (100 g/l, CO₂-free water)clear and not more intense in color than reference solution BY₆
Solubilitypasses test
pH-value (1 g/l in CO₂-free Water)9.5 - 10.5
Chloride (Cl)≤ 350 ppm
Sulfate (SO₄)≤ 300 ppm
Related substances (HPLC, Ph. Eur.)passes test
4-Hydroxy benzoic acid (Ph. Eur.)≤ 3.0 %
Sum of all impurities (without 4-Hydroxybenzoic acid (Ph.Eur.))≤ 1.0 %
Largest unspecified impurity (Ph.Eur.)≤ 0.5 %
Related substances (HPLC, NF)passes test
4-Hydroxy benzoic acid (NF)≤ 3.0 %
Sum of all impurities (without 4-Hydroxybenzoic acid (NF))≤ 1.0 %
Largest unspecified impurity (NF)≤ 0.5 %
Methanol (HS-GC)≤ 3000 ppm
Other residual solvents (ICH Q3C)excluded by manufactoring process
Water (according to Karl Fischer)≤ 5.0 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds Ph Eur, BP,NF
Global Trade Item Number
Catalogue Number GTIN
1.06756.5000 04022536081809

Documentation

Material Qualification Dossier

TitleVersion
9.0

Quality Management Dossier (Open Access)

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Operational Excellence Dossier

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Methyl 4-hydroxybenzoate sodium salt SDS

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Safety Data Sheet (SDS) 

Methyl 4-hydroxybenzoate sodium salt Certificates of Analysis

Product Number PackagingSpecificationLot Number
1.06756.5000 Plastic bottlePDF Specification Document

Certificates

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