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444286 MMP-2 Inhibitor II - CAS 869577-51-5 - Calbiochem

444286
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Overview

Key Spec Table

CAS #Empirical Formula
869577-51-5C₁₆H₁₇NO₆S₂

Products

Catalogue NumberPackaging Qty/Pack
444286-5MGCN Plastic ampoule 5 mg
Description
OverviewAn oxirane analog of SB-3CT, pMS (Cat. No. 444285) that acts as a selective, active site-binding, irreversible inhibitor of MMP-2 (Ki = 2.4 µM). Although less potent, it exhibits enhanced selectivity towards MMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively) than SB-3CT, pMS.
Catalogue Number444286
Brand Family Calbiochem®
Synonyms(4-(4-(Methanesulfonamido)phenoxy)phenylsulfonyl)methyloxirane
References
ReferencesIkejiri, M., et al. 2005. J. Biol. Chem. 280, 33992.
Product Information
CAS number869577-51-5
FormWhite solid
Hill FormulaC₁₆H₁₇NO₆S₂
Chemical formulaC₁₆H₁₇NO₆S₂
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetMMP-2
Primary Target K<sub>i</sub>2.4 µM
Secondary targetMMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively)
Purity≥97% by HPLC
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
444286-5MGCN 04055977186031