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444190 MAP Kinase Inhibitor Set II - Calbiochem

The MAP Kinase Inhibitor Set II controls the biological activity of MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MAP Kinase Inhibitor Set II - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: MAP kinase
444190
Purchase on Sigma-Aldrich

Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
444190-1SETCN Glass bottle 1 set
Description
OverviewContains 5 mg of PD 98059 (Cat. No. 513000), 1 mg each of SB 203580 (Cat. No. 559389), and U0126 (Cat. No. 662005), and 1 mg of Proteasome Inhibitor I (Cat. No. 539160), which serves as a negative control.
Catalogue Number444190
Brand Family Calbiochem®
References
Product Information
FormSolid
Quality LevelMQ100
Applications
Biological Information
Primary TargetMAP kinase
Primary Target IC<sub>50</sub>2 µM
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze
(-20°C).
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
444190-1SETCN 04055977205541

Documentation

MAP Kinase Inhibitor Set II - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

MAP Kinase Inhibitor Set II - Calbiochem Certificates of Analysis

TitleLot Number
444190

Brochure

Title
Protein Kinase Assay and Detection Kits Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision26-August-2020 JSW
DescriptionThe Mitogen-activated protein kinases (MAP Kinases) are a group of protein serine/threonine kinases that are activated in response to a variety of extracellular stimuli and mediate signal transduction from the cell surface to the nucleus. MAP kinases, in combination with several other signaling pathways can differentially alter phosphorylation status of the transcription factors that is unique to a given signal from outside the cell. A controlled regulation of these cascades is involved in cell proliferation and differentiation, whereas an unregulated activation of these MAP kinases can result in oncogenesis. Three major types of MAP kinase cascades have been reported in mammalian cells that respond synergistically to different upstream signals. They are ERK1/ERK2 MAP kinases, the JNK/SAPK (c-Jun kinase/stress activated protein kinase), and the p38 kinase.

The Calbiochem® MAP Kinase Inhibitor Set II contains 4 inhibitors with different MAP Kinase specificities for your convenience.
FormSolid
Intert gas (Yes/No) Packaged under inert gas
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze
(-20°C).
Toxicity Standard Handling