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101544 L-Arginine monohydrochloride

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
1119-34-2214-275-1C₆H₁₄N₄O₂˙ ClHC₆H₁₄N₄O₂*HCl210.67 g/molPh Eur,BP,ChP,JP,USP

Products

Catalogue NumberPackaging Qty/Pack
1.01544.0001 Plastic bottle 3 x 1 kg
1.01544.1000 Plastic bottle 1 kg
1.01544.5000 Plastic drum 5 kg
1.01544.9010 Plastic drum 10 kg
1.01544.9026 Plastic drum 25 kg
Description
Catalogue Number101544
Synonymsa-Amino-d-guanidino valerianic acid hydrochloride, alpha-Amino-delta-guanidino valerianic acid hydrochloride, Arg, α-Amino-δ-guanidino valerianic acid hydrochloride
DescriptionL-Arginine monohydrochloride
References
Product Information
CAS number1119-34-2
EC number214-275-1
GradePh Eur,BP,ChP,JP,USP
Hill FormulaC₆H₁₄N₄O₂˙ ClH
Chemical formulaC₆H₁₄N₄O₂*HCl
Molar Mass210.67 g/mol
HS Code2925 29 19
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Density1.42 g/cm3 (20 °C)
Melting Point>235 °C
pH value5.5 - 7 (211 g/l, H₂O, 25 °C)
Vapor pressure<0.1 Pa (20 °C)
Bulk density1250 kg/m3
Solubility730 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat 12000 mg/kg
Safety Information according to GHS
RTECSCF1995500
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +30°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Assay (perchloric acid titration, calculated on dried substance)98.5 - 101.0 %
Identity (IR-spectrum)passes test
Identity (wet chemistry)passes test
Identity (specific rotation)passes test
Identity (TLC)passes test
Appearancewhite to almost white or colorless, irregular crystals
Appearance of solution (50 g/l; water)clear and not more intense in color than reference solution BY₆
Appearance of solution (100 g/l, water)clear and colorless
Transmittance of solution (100 g/l, water)≥ 98.0 %
pH (100 g/l, CO₂-free water)4.7 - 6.2
Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 250 g/l, calc. on dried substance)+21.0 to +23.5
Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+21.5 to +23.5
Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 6 mol/l,previously dried substance)+21.5 to +23.5
Chloride (Cl) (argentometric)16.5 - 17.1 %
Chloride (argentometric, calc. on dried substance)16.5 - 17.1 %
Proteinspasses test
Sulfate (SO₄)≤ 200 ppm
Phosphate (PO43-)≤ 200 ppm
Heavy metals (as Pb)≤ 10 ppm
As (Arsenic)≤ 1 ppm
Fe (Iron)≤ 10 ppm
Other amino acids (TLC)≤ 0.2 %
Related Compounds, total (TLC)≤ 0.5 %
Related substances (TLC)passes test
Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.2 %
Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
Ninhydrin-positive substances (LC) (total impurities)≤ 0.5 %
Residual solvents (ICH Q3C)excluded by manufacturing process
Sulfated ash (600 °C)≤ 0.1 %
Loss on drying (105 °C, 2 h)≤ 0.20 %
Bacterial endotoxins≤ 3.0 I.U./g
Bacterial endotoxins (ChP)≤ 3.0 I.U./g
Microbiological test (total aerobic microbial count (TAMC))≤ 10²
Microbiological test (total yeast and mould count (TYMC))≤ 10¹
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Compliance with pyrogens (according to ChP) is guaranteed by the test for bacterial endotoxins (ChP) and the production process.
Corresponds to Ph. Eur., BP, ChP, JP, USP.
Global Trade Item Number
Catalogue Number GTIN
1.01544.0001 04027269365158
1.01544.1000 04022536022512
1.01544.5000 04022536732596
1.01544.9010 04022536706757
1.01544.9026 04054839392115

Documentation

Material Qualification Dossier

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10.0

Quality Management Dossier (Open Access)

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Operational Excellence Dossier

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L-Arginine monohydrochloride SDS

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Safety Data Sheet (SDS) 

L-Arginine monohydrochloride Certificates of Analysis

Product Number PackagingSpecificationLot Number
1.01544.0001 Plastic bottlePDF Specification Document
1.01544.1000 Plastic bottlePDF Specification Document
1.01544.5000 Plastic drumPDF Specification Document
1.01544.9010 Plastic drumPDF Specification Document
1.01544.9026 Plastic drumPDF Specification Document

Certificates

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