584223 Sigma-AldrichInSolution™ Tetrahydrouridine - CAS 18771-50-1 - Calbiochem
Tetrahydrouridine is a potent competitive inhibitor of cytidine deaminase.
More>> Tetrahydrouridine is a potent competitive inhibitor of cytidine deaminase. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one, dihydrate, THU, H4U
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Overview
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Key Spec Table
| CAS # | Empirical Formula |
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| 18771-50-1 | C₉H₁₆N₂O₆ • 2H₂O |
Products
| Catalogue Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 584223-25MGCN | Glass bottle | 25 mg |
| Description | |
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| Overview | A potent competitive inhibitor of cytidine deaminase. Used in combination with cytosine arabinoside (Ara-C) to assess the anti-leukemic activity and anti-tumor activity of Ara-C in in vitro studies. The solid form of this compound (Cat. No. 584222) is also available. |
| Catalogue Number | 584223 |
| Brand Family | Calbiochem® |
| Synonyms | 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one, dihydrate, THU, H4U |
| Product Information | |
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| CAS number | 18771-50-1 |
| Form | Liquid |
| Formulation | A 100 mM (25 mg/879 µL) solution of Tetrahydrouridine (Cat. No. 584222) in H₂O. |
| Hill Formula | C₉H₁₆N₂O₆ • 2H₂O |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | cytidine deaminase |
| Purity | ≥90% by TLC |
| Physicochemical Information | |
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| Cell permeable | Y |
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| Safety Information according to GHS |
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| Safety Information |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 584223-25MGCN | 04055977264999 |
Documentation
InSolution™ Tetrahydrouridine - CAS 18771-50-1 - Calbiochem SDS
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InSolution™ Tetrahydrouridine - CAS 18771-50-1 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 584223 |
References
| Reference overview |
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| Yusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486. Bouffard, D.Y., et al. 1993. Biochem Pharmacol. 45, 1857. Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol. 30, 7. Riva, C., et al. 1992. Chemotherapy 38, 358. Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848. Hanze, A.R. 1967. J. Am. Chem. Soc. 89, 6720. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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