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324904 Epiregulin, Mouse, Recombinant

Epiregulin, Mouse, Recombinant is expressed in E. coli with an N-terminal methionine. Inhibits epithelial tumor growth and stimulates the growth of fibroblasts and other cell types.

Epiregulin, Mouse, Recombinant MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
324904
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Overview

Replacement Information

Key Spec Table

Purity
≥97% by SDS-PAGE

Products

Catalogue NumberPackaging Qty/Pack
324904-50UGCN Glass bottle 50 μg
Description
OverviewRecombinant, mouse epiregulin expressed in E. coli with an N-terminal methionine. Epiregulin is shown to inhibit epithelial tumor growth, able to stimulate growth of fibroblasts and other cell types, and has been shown to be an autocrine growth factor in human epidermal keratinocytes.
Catalogue Number324904
Brand Family Calbiochem®
References
ReferencesShirakata, Y., et al. 2000. J. Biol. Chem. 275, 5748.
Shelly, M., et al. 1998. J. Biol. Chem. 273, 10496.
Das, S.K., et al. 1997. Dev. Biol. 190, 178.
Komurasaki, T., et al. 1997. Oncogene 15, 2841.
Toyoda, H., et al. 1995. J. Biol. Chem. 270, 7495.
Toyoda, H., et al. 1995. FEBS Lett. 377, 403.
Product Information
FormLiquid
FormulationLyophilized from 0.2 µm sterile-filtered PBS, BSA.
Quality LevelMQ100
Applications
Biological Information
Biological activityED₅₀ = 0.3-1 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.
Purity≥97% by SDS-PAGE
Physicochemical Information
ContaminantsEndotoxin: <1.0 EU/µg protein
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
324904-50UGCN 04055977196276

Documentation

Epiregulin, Mouse, Recombinant SDS

Title

Safety Data Sheet (SDS) 

Epiregulin, Mouse, Recombinant Certificates of Analysis

TitleLot Number
324904

References

Reference overview
Shirakata, Y., et al. 2000. J. Biol. Chem. 275, 5748.
Shelly, M., et al. 1998. J. Biol. Chem. 273, 10496.
Das, S.K., et al. 1997. Dev. Biol. 190, 178.
Komurasaki, T., et al. 1997. Oncogene 15, 2841.
Toyoda, H., et al. 1995. J. Biol. Chem. 270, 7495.
Toyoda, H., et al. 1995. FEBS Lett. 377, 403.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision21-Sepmtember-2011 RFH
DescriptionRecombinant, mouse epiregulin expressed in E. coli with an N-terminal methionine. Epiregulin is shown to inhibit epithelial tumor growth, able to stimulate growth of fibroblasts and other cell types, and has been shown to be an autocrine growth factor in human epidermal keratinocytes.
FormLiquid
FormulationLyophilized from 0.2 µm sterile-filtered PBS, BSA.
Purity≥97% by SDS-PAGE
ContaminantsEndotoxin: <1.0 EU/µg protein
Biological activityED₅₀ = 0.3-1 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.
SolubilityReconstitute to 10 µg/ml in sterile PBS containing at least 0.1% human or bovine serum albumin.
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesShirakata, Y., et al. 2000. J. Biol. Chem. 275, 5748.
Shelly, M., et al. 1998. J. Biol. Chem. 273, 10496.
Das, S.K., et al. 1997. Dev. Biol. 190, 178.
Komurasaki, T., et al. 1997. Oncogene 15, 2841.
Toyoda, H., et al. 1995. J. Biol. Chem. 270, 7495.
Toyoda, H., et al. 1995. FEBS Lett. 377, 403.