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14-692M DAPK1 Protein, active, 250 µg

Active, N-terminal GST-tagged, recombinant, human DAPK1, amino acids 1-296, for use in Kinase Assays.

DAPK1 Protein, active, 250 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
14-692M
250 µg  Also available in 10 μg size (cat#14-692) and in bulk (cat# 14-692-K).
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number14-692M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionDAPK1 Protein, active, 250 µg
OverviewN-terminal GST-tagged, recombinant, human DAPK1, amino acids 1-296
References
Product Information
Quality LevelMQ300
Applications
ApplicationActive, N-terminal GST-tagged, recombinant, human DAPK1, amino acids 1-296, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Sourceexpressed by baculovirus in Sf21 cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
Entrez Gene Number
Entrez Gene SummaryDeath-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate.
Gene Symbol
  • DAPK1
  • DAPK
  • DKFZp781I035
Protein TargetDAPK1
Purification MethodGlutathione agarose affinity chromatography
Target Sub-FamilyCAMK
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P53355 # Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis.
COFACTOR: Magnesium.
SIZE: 1432 amino acids; 160286 Da
SUBCELLULAR LOCATION: Cytoplasm. Note=Colocalizes with the actin filament system.
SIMILARITY: SwissProt: P53355 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily. & Contains 10 ANK repeats. & Contains 1 death domain. & Contains 1 protein kinase domain.
Molecular Weight60.9kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assuranceroutinely evaluated by phosphorylation of ZIPtide (Catalog #12-545)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditionsstable 6 months at -70°C from date of shipment
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-692) and in bulk (cat# 14-692-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
14-692M 04053252368691

Related Products & Applications

Alternative Packsize

Catalogue Number Description
14-692 DAPK1 Protein, active, 10 µg

Product Families

Kinase & Phosphatase Products

Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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Categories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases