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SCT260 BioTracker™ Green Lipid Peroxide Live Cell Ferroptosis Indicator

This perylene derivative probe containing oligooxyethylene is designed for the detection of lipid peroxides in live cells.

SCT260
250 μg  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue NumberSCT260
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DescriptionBioTracker™ Green Lipid Peroxide Live Cell Ferroptosis Indicator
OverviewThis perylene derivative probe containing oligooxyethylene is designed for detection of lipid peroxides. BioTracker™ Green Lipid Peroxide Live Cell Ferroptosis Indicator emits intense fluorescence by lipid peroxide specific oxidation in organic solvents such as ethanol. This is the only RUO probe that can specifically detect lipid peroxides.
SCT260's oxidized form is nearly nonfluorescent in an aqueous media, but produces a bright fluorescence in lipophilic sites such as in cell membranes.

This probe is light-sensitive, and should be pipetted as quickly as possible, preferably within one minute. Protect working solutions and samples from light, and use within one day of preparing working solution.
Alternate Names
  • lipid peroxide probe
  • lipid peroxide live cell dye
  • live cell ferroptosis indicator
Background InformationThis perylene derivative containing oligooxyethylene is designed for the detection of lipid peroxides. SCT260 emits intense fluorescence by lipid peroxide-specific oxidation in organic solvents such as ethanol. Among fluorescent probes that detect Reactive Oxygen Species(ROS), SCT260 is the only compound that can specifically detect lipid peroxides. Because the excitation and emission wavelengths of the oxidized probe are 524 nm and 535 nm, respectively, phototoxicity to and autofluorescence from the sample can be minimized. The tetraethyleneglycol group linked to one end of diisoquinoline ring enhances solubility and dispersibility in aqueous buffer.
References
Product Information
Detection methodFluorescence
FormatLyophilized solid
PresentationLyophilized. Dark red solid.
Quality LevelMQ100
Applications
ApplicationThis perylene derivative probe containing oligooxyethylene is designed for the detection of lipid peroxides in live cells.
Key Applications
  • Cell Based Assays
  • Fluorescence
  • Flow Cytometry
  • Fluorescence Activated Cell Sorting (FACS)
Application NotesLive cell probe for fluorescent detection of lipid peroxidation by fluorescence microscopy or flow cytometry. SCT260 is a valuable reagent for ferroptosis research.
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance
Purity: ≥ 90% confirmed by HPLC. Authenticated by NMR.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore BioTracker™ Green Lipid Peroxide Live Cell Ferroptosis Indicator at 2 - 8 °C, protected from light.
Packaging Information
Material Size250 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
SCT260 04065269218135

Documentation

BioTracker™ Green Lipid Peroxide Live Cell Ferroptosis Indicator SDS

Title

Safety Data Sheet (SDS)