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05-23-0300 Atrial Natriuretic Factor 1-28, Human - CAS 91917-63-4 - Calbiochem

Atrial Natriuretic Factor 1-28, CAS 91917-63-4, increases the rate of renal excretion. Higher levels are reported in congestive heart failure. Involved in diuresis and blood pressure regulation.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: hANF, ANP, SLRRSSCFGGRMDRIGAQSGLGCNSFRY

Primary Target: Increases the rate of renal excretion
05-23-0300
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
91917-63-4C₁₂₇H₂₀₃N₄₅O₃₉S₃

Products

Catalogue NumberPackaging Qty/Pack
05-23-0300-0.5MGCN Plastic ampoule .5 mg
05-23-0300-1MGCN Plastic ampoule 1 mg
Description
OverviewIncreases the rate of renal excretion. Higher levels are reported in congestive heart failure. Inhibits MAP kinase through the natriuretic peptide clearance receptor.
Catalogue Number05-23-0300
Brand Family Calbiochem®
SynonymshANF, ANP, SLRRSSCFGGRMDRIGAQSGLGCNSFRY
References
ReferencesPrins, B.A., et al. 1996. J. Biol. Chem. 271, 14156.
Yechieli, H., et al. 1993. Am. J. Physiol. 265, F119.
Product Information
CAS number91917-63-4
ATP CompetitiveN
FormWhite to off-white lyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₁₂₇H₂₀₃N₄₅O₃₉S₃
Chemical formulaC₁₂₇H₂₀₃N₄₅O₃₉S₃
Hygroscopic Hygroscopic
ReversibleN
Sold on the basis of peptide contentY
Quality LevelMQ100
Applications
Biological Information
Primary TargetIncreases the rate of renal excretion
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Peptide ContentY
Peptide SequenceH-Ser-Leu-Arg-Arg-Ser-Ser-Cys⁷-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys²³-Asn-Ser-Phe-Arg-Tyr-OH (disulfide bond: 7 → 23)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
05-23-0300-0.5MGCN 04055977206944
05-23-0300-1MGCN 04055977206951

Documentation

Atrial Natriuretic Factor 1-28, Human - CAS 91917-63-4 - Calbiochem Certificates of Analysis

TitleLot Number
05-23-0300

References

Reference overview
Prins, B.A., et al. 1996. J. Biol. Chem. 271, 14156.
Yechieli, H., et al. 1993. Am. J. Physiol. 265, F119.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision18-September-2008 RFH
SynonymshANF, ANP, SLRRSSCFGGRMDRIGAQSGLGCNSFRY
DescriptionIncreases the rate of renal excretion. Higher levels are reported in congestive heart failure. Inhibits MAP kinase through the clearance receptor.
FormWhite to off-white lyophilized solid
FormulationSupplied as a trifluoroacetate salt.
CAS number91917-63-4
Chemical formulaC₁₂₇H₂₀₃N₄₅O₃₉S₃
Peptide SequenceH-Ser-Leu-Arg-Arg-Ser-Ser-Cys⁷-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys²³-Asn-Ser-Phe-Arg-Tyr-OH (disulfide bond: 7 → 23)
Purity≥97% by HPLC
Solubility5% acetic acid (1 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity Standard Handling
Merck USA index14 1360
ReferencesPrins, B.A., et al. 1996. J. Biol. Chem. 271, 14156.
Yechieli, H., et al. 1993. Am. J. Physiol. 265, F119.