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MABN762 Anti-VSNL1 Antibody, clone 2D11

Detect VSNL1 using this Anti-VSNL1 Antibody, clone 2D11 validated for use in western blotting & IHC.

Anti-VSNL1 Antibody, clone 2D11 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: VSNL1, VISL1 UniProt Number: P62760
MABN762
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, R, H, BWB, IHCMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN762
DescriptionAnti-VSNL1 Antibody, clone 2D11
Alternate Names
  • Visinin-like protein 1
  • VILIP
  • VLP-1
  • Hippocalcin-like protein 3
  • HLP3
Background InformationThe protein VSNL1, Visinin-like protein 1 (VILIP, or VLP-1), or Hippocalcin-like protein 3 (HLP3) and encoded by the gene VSNL1/VISL1, is a calcium sensor protein that regulates calcium signaling pathways in neurons. In the retina VSNL1 regulates the inhibition of rhodopsin phosphorylation. VSNL1 is expressed specifically in the brain (and is particularly strong in the granule cells of the cerebellum), retina and PNS. VSNL1 levels are up regulated in Alzheimer's disease but the significance is unknown at present. VSNL1 belongs to the recoverin family of neuronal specific proteins. Interestingly, new research seems so argue that VSHL1 can also be expressed by non-neuronal cells such as epidermal cells and may play a role as a tumor suppressor gene in squamous carcinoma cells and skin cancer.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG2bκ in buffer containing PBS with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect VSNL1 using this Anti-VSNL1 Antibody, clone 2D11 validated for use in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesWestern Blotting Analysis: 0.5 µg/mL from a representative lot detected VSNL1 in 10 µg of human cerebellum, rat brain, and mouse cerebellum tissue lysate.
Immunohistochemistry Analysis: A representative lot detected VSNL1 in rat cerebellar cortex tissue (courtesy from the laboratory of Gerry Shaw).
Biological Information
ImmunogenRecombinant protein corresponding to human VSNL1.
Clone2D11
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG2bκ
Species Reactivity
  • Mouse
  • Rat
  • Human
  • Bovine
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • VSNL1
  • VISL1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~22 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected VSNL1 in 10 µg of mouse brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABN762 04053252956126