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662045 Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb

662045
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Species ReactivityHostAntibody Type
H, M, RRbPolyclonal Antibody

Products

Catalogue NumberPackaging Qty/Pack
662045-100ULCN Plastic ampoule 100 ul
Description
OverviewRecognizes the UCP-1 protein.
Catalogue Number662045
Brand Family Calbiochem®
References
ReferencesKozak, L.P., et al. 1988. J. Biol. Chem. 263, 12274.
Product Information
FormLiquid
FormulationIn PBS.
PreservativeNone
Quality LevelMQ100
Applications
Key Applications Immunoblotting (Western Blotting)
Application NotesImmunoblotting (1:1000)
Application CommentsDoes not exhibit cross-reactivity with UCP2 or UCP3. Since this antigen sequence is highly conserved, cross-reactivity across a broad range of species is expected. Variables associated with assay conditions will dictate the proper working dilution.
Biological Information
Immunogena synthetic peptide [(C)SHLHGIKPRYTGTYN] corresponding to amino acids 145-159 of mouse UCP1
ImmunogenMouse
HostRabbit
IsotypeIgG
Species Reactivity
  • Human
  • Mouse
  • Rat
Antibody TypePolyclonal Antibody
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
662045-100ULCN 04055977261073

Documentation

Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb SDS

Title

Safety Data Sheet (SDS) 

Anti-Uncoupling Protein-1 (UCP-1) (145-159) Rabbit pAb Certificates of Analysis

TitleLot Number
662045

References

Reference overview
Kozak, L.P., et al. 1988. J. Biol. Chem. 263, 12274.

Citations

Title
  • Michael Koban and Kevin L. Swinson. (2005) Chronic REM-sleep deprivation of rats elevates metabolic rate and increases UCP1 gene expression in brown adipose tissue. American Journal of Physiology Endocrinology and Metabolism 289, E68-E74.
  • Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision16-August-2007 RFH
    ApplicationImmunoblotting (1:1000)
    DescriptionProtein A purified rabbit polyclonal antibody. Recognizes the UCP-1 protein.
    BackgroundUncoupling protein-1 (UCP-1) is essential for the thermogenic properties of brown fat in mammals. It is inserted in the inner mitochondrial membrane by means of six α-helical hydrophobic transmembrane domains.
    HostRabbit
    Immunogen speciesMouse
    Immunogena synthetic peptide [(C)SHLHGIKPRYTGTYN] corresponding to amino acids 145-159 of mouse UCP1
    IsotypeIgG
    Specieshuman, mouse, rat
    FormLiquid
    FormulationIn PBS.
    PreservativeNone
    CommentsDoes not exhibit cross-reactivity with UCP2 or UCP3. Since this antigen sequence is highly conserved, cross-reactivity across a broad range of species is expected. Variables associated with assay conditions will dictate the proper working dilution.
    Storage Avoid freeze/thaw
    ≤ -70°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
    Toxicity Standard Handling
    ReferencesKozak, L.P., et al. 1988. J. Biol. Chem. 263, 12274.
    Citation
  • Michael Koban and Kevin L. Swinson. (2005) Chronic REM-sleep deprivation of rats elevates metabolic rate and increases UCP1 gene expression in brown adipose tissue. American Journal of Physiology Endocrinology and Metabolism 289, E68-E74.