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ABE531 Anti-PRDM1 Antibody

ABE531
100 µL  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABE531
DescriptionAnti-PRDM1 Antibody
Alternate Names
  • PRDM1
  • PR domain zinc finger protein 1
  • BLIMP-1
  • Beta-interferon gene positive regulatory domain I-binding factor
  • PR domain-containing protein 1
  • Positive regulatory domain I-binding factor 1
  • PRDI-BF1
  • PRDI-binding factor 1
Background InformationPR domain zinc finger protein 1 (also known as Beta-interferon gene positive regulatory domain I-binding factor, BLIMP-1, Positive regulatory domain I-binding factor 1, PRDI-BF1, PRDI-binding factor 1, PR domain-containing protein 1) is a transcriptional repressor encoded by the PRDM1 gene (or BLIMP1; Entrez Gene ID 639) in human. PRDM1/PLIMP1 protein silences target genes expression collaboratively with several chromatin-modifying enzymes as co-repressors, including histone deacetylases HDAC1/2, lysine methyltransferase G9a, protein arginine methyltransferase PRMT5, lysine-specific demethylase LSD1, as well as Groucho/Transducin-Like Enhancer of split (Gro/TLE) family of co-repressors. Prdm1/Blimp-1 contains an N-terminal PR/SET domain, a central proline- and serine-rich region, and 5 carboxy-terminal zinc fingers. Cat. No. ABE531, Anti-PRDM1.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ300
Applications
ApplicationAnti-PRDM1 Antibody is an antibody against PRDM1 for use in Western Blotting.
Key Applications
  • Western Blotting
Application NotesWestern Blotting Analysis: A 1:125 dilution from a representative lot detected PRDM1 in 10 µg of HL-60 cell lysate.
Biological Information
ImmunogenHis-tagged recombinant protein corresponding to human PRDM1.
EpitopeUnknown
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • PRDM1
  • BLIMP1
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~105 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in SR cell lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected PRDM1 in 10 µg of SR cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABE531 04055977163964