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MAB5260Z Anti-Nerve Growth Factor Antibody, clone 27/21, azide free

MAB5260Z
25 µg  
Purchase on Sigma-Aldrich

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Overview

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
B, H, M, RELISA, NEUTMPurifiedMonoclonal Antibody
Description
Catalogue NumberMAB5260Z
Replaces04-1119
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Nerve Growth Factor Antibody, clone 27/21, azide free
Alternate Names
  • NGF
  • MAB5260
Product Information
FormatPurified
Control
  • Brain tissue
PresentationProtein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with no preservatives.
Quality LevelMQ100
Applications
ApplicationDetect Nerve Growth Factor using this Anti-Nerve Growth Factor Antibody, clone 27/21, azide free validated for use in ELISA, NEUT.
Key Applications
  • ELISA
  • Neutralizing
Application NotesThe antibody is used for the neutralization of NGF in cell culture systems. Furthermore the antibody is used to immunosympathectomy.

Optimal working dilutions must be determined by end user.
Biological Information
Immunogen2.5 S form of mouse NGF.
Clone27/21
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificitySpecifically reacts with the beta -subunit of NGF from mouse, in the 2.5S- as well as in the 7S-form.
IsotypeIgG1
Species Reactivity
  • Bovine
  • Human
  • Mouse
  • Rat
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
Gene Symbol
  • NTF3
  • NT3
  • NGF2
  • HDNF
  • MGC129711
  • NGF-2
  • NT-3
Purification MethodProtein A Purfied
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P20783 # Seems to promotes the survival of visceral and proprioceptive sensory neurons.
SIZE: 257 amino acids; 29355 Da
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Brain and peripheral tissues.
SIMILARITY: SwissProt: P20783 ## Belongs to the NGF-beta family.
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain for 6 months at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Packaging Information
Material Size25 µg
Global Trade Item Number
Catalogue Number GTIN
MAB5260Z 04053252316821