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ABF288 Anti-NOD4 Antibody

ABF288
100 µg  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, ICC, IFRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABF288
DescriptionAnti-NOD4 Antibody
Alternate Names
  • Protein NLRC5
  • Caterpiller protein 16.1
  • CLR16.1
  • Nucleotide-binding oligomerization domain protein 27
  • Nucleotide-binding oligomerization domain protein 4
Background InformationProtein NLRC5, also known as Caterpiller protein 16.1 (CLR16.1) or Nucleotide-binding oligomerization domain protein 27 or Nucleotide-binding oligomerization domain protein 4, and encoded by the gene name NLRC5 or NOD4 or NOD27, may play an important role in regulating the type II interferon signaling pathway. NOD4 is expressed in spleen, thymus, lung, brain, tonsil, heart and prostate. NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-NOD4 Antibody is an antibody against NOD4 for use in western blotting, ICC & immunofluorescence.
Key Applications
  • Western Blotting
  • Immunocytochemistry
  • Immunofluorescence
Application NotesImmunocytochemistry Analysis: 10 μg/mL from a representative lot detected NOD4 in HeLa cells.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected NOD4 in HeLa cells.



Biological Information
ImmunogenKLH-conjugated synthetic peptide corresponding to the N-terminus of human NOD4.
EpitopeN-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
  • Mouse
Antibody TypePolyclonal Antibody
Gene Symbol
  • NLRC5
  • NOD27
  • NOD4
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~205 kDa observed. Uncharacterized bands may be observed in some lysate(s). Uniprot describes 6 isoforms produced by alternative splicing ranging between ~79 kDa and ~206 kDa.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in EL4 cell lysate.

Western Blotting Analysis: 1 μg/mL of this antibody detected NOD4 in EL4 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABF288 04053252946677