Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

ABC336 Anti-MORF4 Antibody

Anti-MORF4 Antibody is a highly specific rabbit polyclonal antibody, that targets Mortality factor 4 & has been tested in western blotting, IHC & Immunofluorescence.

Anti-MORF4 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional UniProt Number: Q9UBU8
ABC336
100 µg  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Special Offers

100% Performance Guaranteed

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHC, IFRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABC336
DescriptionAnti-MORF4 Antibody
Alternate Names
  • MORF4 Antibody
  • MORF4
  • Mortality factor 4
  • Cellular senescence-related protein 1
  • SEN1
Background InformationMortality factor 4 (MORF4) is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes typically by acetylation of nucleosomal histones H4 and H2A. NuA4 complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, DNA repair and apoptosis. MORF4 is localized to the nucleus and has transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif. Additionally, MORF4 has been shown to bind to the transcription corepressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.
References
Product Information
FormatAffinity Purified
Control
  • K562 cell lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-MORF4 Antibody is a highly specific rabbit polyclonal antibody, that targets Mortality factor 4 & has been tested in western blotting, IHC & Immunofluorescence.
Key Applications
  • Western Blotting
  • Immunohistochemistry
  • Immunofluorescence
Application NotesImmunohistochemistry Analysis: 5 µg/mL from a representative lot detected MORF4 in human brain tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected MORF4 in HepG2 cells.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human MORF4.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~33 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in K562 cell lysate

Western Blotting Analysis: 2 µg/mL of this antibody detected MORF4 in 15 µg of K562 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABC336 04053252901355