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ABN442 Anti-FGF-20 Antibody

ABN442
100 µg  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN442
DescriptionAnti-FGF-20 Antibody
Alternate Names
  • Fibroblast growth factor 20
  • FGF-20
Background InformationFGF-20 is a recent but important neurotrophic factor that regulates multiple central nervous system developmental systems and cell functions. It is a secreted protein expressed most highly in the cerebellum but also found in other regions. FGF-20 is a pro-survival factor on neurons and specifically has been shown to protect dopaminergic neurons against a range of toxic insults in vitro, through activation of fibroblast growth factor receptor 1 (FGFR1). FGF-20 treatments also appear to protect neurons in various disease models so it is being studied as a possible therapy.
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-FGF-20 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of FGF-20.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected FGF-20 in human cerebral cortex, human cerebellum, and human thalamus tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human FGF-20 near theC-terminal.
EpitopeNear C-terminal
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
Species Reactivity
  • Human
Species Reactivity NoteHuman. Predicted to react with Mouse, Rat, Guinea Pig, Ferret based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • FGF20
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~30 kDa observed. Uncharacterized band(s) may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in transfected HEK293 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected FGF-20 in 10 µg of transfected HEK293 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABN442 04055977052008