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AB9141 Anti-Dopamine Receptor D1 Antibody

AB9141
50 µg  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HIH(P)RbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB9141
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Dopamine Receptor D1 Antibody
References
Product Information
FormatAffinity Purified
HS Code3002 15 90
PresentationAffinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-Dopamine Receptor D1 Antibody is validated for use in IH(P) for the detection of Dopamine Receptor D1.
Key Applications
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry on formalin fixed paraffin embedded tissue sections.

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenSynthetic peptide from the C-terminal domain of human Dopamine Receptor D1. The immunogen has 94% conservation with rat and 88% with mouse.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityRecognizes Dopamine Receptor D1.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThis gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
Gene Symbol
  • DRD1
  • D
  • DRD1A
  • DADR
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P21728 # This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
SIZE: 446 amino acids; 49293 Da
SUBUNIT: Interacts with DNAJC14 via its C-terminus (By similarity). Interacts with DRD1IP.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity). Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Note=Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14 (By similarity).
TISSUE SPECIFICITY: Detected in caudate, nucleus accumbens and in the olfactory tubercle.
SIMILARITY: SwissProt: P21728 ## Belongs to the G-protein coupled receptor 1 family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Availability by Geography
  • This product is not available for sale in Japan.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size50 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB9141 04053252338298

Documentation

Anti-Dopamine Receptor D1 Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-Dopamine Receptor D1 Antibody Certificates of Analysis

TitleLot Number
RABBIT ANTI- DOPAMINE RECEPTOR D1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2119725 2119725
RABBIT ANTI- DOPAMINE RECEPTOR D1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2135074 2135074
RABBIT ANTI- DOPAMINE RECEPTOR D1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2446677 2446677
RABBIT ANTI- DOPAMINE RECEPTOR D1 - 4068691 4068691
RABBIT ANTI- DOPAMINE RECEPTOR D1 -2576349 2576349
RABBIT ANTI- DOPAMINE RECEPTOR D1 -2774139 2774139
RABBIT ANTI- DOPAMINE RECEPTOR D1 -2776257 2776257
RABBIT ANTI- DOPAMINE RECEPTOR D1 AFFINITY PURIFIED POLYCLONAL ANTIBODY 2990631
RABBIT ANTI- DOPAMINE RECEPTOR D1 AFFINITY PURIFIED POLYCLONAL ANTIBODY 3098888
RABBIT ANTI- DOPAMINE RECEPTOR D1 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 3934415 3934415

Data Sheet

Title
RABBIT ANTI- DOPAMINE RECEPTOR D1