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CBL168F Anti-CD36 Antibody, clone SM-phi, FITC conjugated

This Anti-CD36 Antibody, clone SM-phi, FITC conjugated is validated for use in FC, IH for the detection of CD36d. This antibody has been tested in Human.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: CD36, PAS-4, GPIV, FAT, CHDS7, GP3B, SCARB3, PASIV, GP4, GPIIIB UniProt Number: P16671
CBL168F
100 assays  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HFC, IHCMFITCMonoclonal Antibody
Description
Catalogue NumberCBL168F
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-CD36 Antibody, clone SM-phi, FITC conjugated
Alternate Names
  • Platelet Glycoprotein IV
References
Product Information
FormatFITC
PresentationThe monoclonal was purified by affinity chromatography and gel filtration prior to conjugation. The conjugate is supplied in 1.0 ml of phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. For flow cytometry we recommend using 10μL of conjugate per test.
Quality LevelMQ100
Applications
ApplicationThis Anti-CD36 Antibody, clone SM-phi, FITC conjugated is validated for use in FC, IH for the detection of CD36d. This antibody has been tested in Human.
Key Applications
  • Flow Cytometry
  • Immunohistochemistry
Application NotesStudies of platelet and monocyte receptor for thrombospondin

Studies of platelet collagen adhesion receptor

Flow cytometry

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenHuman tonsil cells and peripheral blood mononuclear cells
CloneSM-phi
HostMouse
SpecificityThis antibody recognizes the 90 kDa single chain membrane glycoprotein (GPIIIb) that is found on monocytes/macrophages and platelets. FUSION PARTNER: NS1 myeloma cell line
IsotypeIgM
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Three alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Gene Symbol
  • CD36
  • PAS-4
  • GPIV
  • FAT
  • CHDS7
  • GP3B
  • SCARB3
  • PASIV
  • GP4
  • GPIIIB
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P16671 # Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport.
SIZE: 472 amino acids; 53053 Da
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
PTM: N-glycosylated and O-glycosylated with a ratio of 2:1.
DISEASE: SwissProt: P16671 # Defects in CD36 are the cause of platelet glycoprotein IV deficiency [MIM:608404]; also known as CD36 deficiency. Platelet glycoprotein IV deficiency can be divided into 2 subgroups. The type I phenotype is characterized by platelets and monocytes/macrophages exhibiting complete CD36 deficiency. The type II phenotype lacks the surface expression of CD36 in platelets, but expression in monocytes/macrophages is near normal. & Genetic variations in CD36 are associated with susceptibility to coronary heart disease type 7 (CHDS7) [MIM:610938].
SIMILARITY: SwissProt: P16671 ## Belongs to the CD36 family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at +4°C protected from light. DO NOT FREEZE. For long term use and storage aliquot conjugate into small volumes and store at +4°C for up to one year.
Packaging Information
Material Size100 assays
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
CBL168F 04053252281228

Documentation

Anti-CD36 Antibody, clone SM-phi, FITC conjugated SDS

Title

Safety Data Sheet (SDS) 

Anti-CD36 Antibody, clone SM-phi, FITC conjugated Certificates of Analysis

TitleLot Number
MOUSE ANTI-HUMAN CD36 FITC 2424780
MOUSE ANTI-HUMAN CD36 FITC CONJUGATED MONOCLONAL ANTIBODY 3043669
MOUSE ANTI-HUMAN CD36 FITC CONJUGATED MONOCLONAL ANTIBODY 3148514
MOUSE ANTI-HUMAN CD36 FITC CONJUGATED MONOCLONAL ANTIBODY - 2398913 2398913
MOUSE ANTI-HUMAN CD36 FITC CONJUGATED MONOCLONAL ANTIBODY - 2045564 2045564
MOUSE ANTI-HUMAN CD36 FITC CONJUGATED MONOCLONAL ANTIBODY - 2193302 2193302
MOUSE ANTI-HUMAN CD36 FITC CONJUGATED MONOCLONAL ANTIBODY - 2207165 2207165
MOUSE ANTI-HUMAN CD36 FITC CONJUGATED MONOCLONAL ANTIBODY - 3194678 3194678
MOUSE ANTI-HUMAN CD36 FITC CONJUGATED MONOCLONAL ANTIBODY - 3318414 3318414
MOUSE ANTI-HUMAN CD36 FITC CONJUGATED MONOCLONAL ANTIBODY - 3817625 3817625
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References

Reference overviewPub Med ID
Membrane glycoprotein CD36: a review of its roles in adherence, signal transduction, and transfusion medicine.
Greenwalt, D E, et al.
Blood, 80: 1105-15 (1992)  1992

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