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05-23-2540 Amylin, Human - CAS 122384-88-7 - Calbiochem

Amylin, Human, CAS 122384-88-7, is a 37-amino acid polypeptide secreted from the β cells of the pancreas. Structurally related to calcitonin. Has anorectic effects in rats.

Amylin, Human - CAS 122384-88-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Islet Amyloid Polypeptide

Primary Target: Has anorectic effects in rats
05-23-2540
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
122384-88-7C₁₆₅H₂₆₁N₅₁O₅₅S₂

Products

Catalogue NumberPackaging Qty/Pack
05-23-2540-0.5MGCN Plastic ampoule 0.5 mg
Description
OverviewA 37-amino acid polypeptide secreted by the β cells of the pancreas. Structurally related to calcitonin. Has anorectic effects in rats. Implicated in the development of type II diabetes through its modulation of peripheral effects of insulin. Blocks the activation of glycogen synthase by insulin.
Catalogue Number05-23-2540
Brand Family Calbiochem®
SynonymsIslet Amyloid Polypeptide
References
ReferencesBaque, S., et al. 1994. Biochem. J. 304, 449.
Lutz, T.A., et al. 1994. Physiol. Behav. 55, 891.
Pittner, R.A., et al. 1994. J. Cell. Biochem. 55 (Suppl.), 19.
Wagoner, P.K., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 145.
Product Information
CAS number122384-88-7
ATP CompetitiveN
DeclarationNot for sale in the United States.
FormWhite to off-white lyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₁₆₅H₂₆₁N₅₁O₅₅S₂
Chemical formulaC₁₆₅H₂₆₁N₅₁O₅₅S₂
ReversibleN
Sold on the basis of peptide contentY
Quality LevelMQ100
Applications
Biological Information
Primary TargetHas anorectic effects in rats
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Peptide ContentY
Peptide SequenceH-Lys-Cys²-Asn-Thr-Ala-Thr-Cys⁷-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH₂ (disulfide bond: 2→7)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
05-23-2540-0.5MGCN 04055977226720

Documentation

Amylin, Human - CAS 122384-88-7 - Calbiochem Certificates of Analysis

TitleLot Number
05-23-2540

References

Reference overview
Baque, S., et al. 1994. Biochem. J. 304, 449.
Lutz, T.A., et al. 1994. Physiol. Behav. 55, 891.
Pittner, R.A., et al. 1994. J. Cell. Biochem. 55 (Suppl.), 19.
Wagoner, P.K., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 145.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision20-June-2017 JSW
SynonymsIslet Amyloid Polypeptide
DescriptionA 37 amino acid polypeptide secreted by the β cells of the pancreas. Structurally related to calcitonin. Has anoretic effects in rats. Implicated in the development of type II diabetes through its modulation of peripheral effects of insulin. Blocks the activation of glycogen synthase by insulin.
FormWhite to off-white lyophilized solid
FormulationSupplied as a trifluoroacetate salt.
CAS number122384-88-7
Chemical formulaC₁₆₅H₂₆₁N₅₁O₅₅S₂
Peptide SequenceH-Lys-Cys²-Asn-Thr-Ala-Thr-Cys⁷-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH₂ (disulfide bond: 2→7)
Purity≥95% by HPLC
Solubility5% acetic acid (1 mg/ml)
Storage Protect from moisture
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity Standard Handling
ReferencesBaque, S., et al. 1994. Biochem. J. 304, 449.
Lutz, T.A., et al. 1994. Physiol. Behav. 55, 891.
Pittner, R.A., et al. 1994. J. Cell. Biochem. 55 (Suppl.), 19.
Wagoner, P.K., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 145.