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MSSACCEPT0R 96 well Collection Plate

MSSACCEPT0R
1  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue NumberMSSACCEPT0R
Trade Name
  • MultiScreen
Description96 well Collection Plate
Background InformationIncreasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates.

MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.

Membranes have uniform pore structure and density for reliable transport:
- Individual wells minimize candidate cross-talk
- Compatibility with automated liquid handling systems increases throughput

Permeability Assay:
- The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1

PAMPA Assay:
- The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3

MultiScreen Acceptor Plate:
- The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.
References
Product Information
Automation CompatibleYes
Color CodeNot Applicable
Number of Wells96
Applications
ApplicationNon-Sterile, reusable, sturdy device made of PTFE, acceptor plate for PAMPA assays, 1 plate
Key Applications
  • PAMPA
Biological Information
SterilityNon-Sterile
Physicochemical Information
Pore SizeNot Applicable
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Packaging Information
Material Size1
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MSSACCEPT0R 04053252267864