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548000 1-Pyrrolidinecarbodithioic Acid, Ammonium Salt - CAS 5108-96-3 - Calbiochem

548000
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Overview

Key Spec Table

CAS #Empirical Formula
5108-96-3C₅H₁₂N₂S₂

Products

Catalogue NumberPackaging Qty/Pack
548000-100MGCN Plastic ampoule 100 mg
Description
OverviewCell permeable. Inhibits the induction of nitric oxide synthase activity in rat alveolar macrophages. Prevents apoptosis in human HL-60 cells and thymocytes, but induces apoptosis in human and rat smooth muscle cells. Inhibits NF-κB activation and HIV replication in lymphocytes.
Catalogue Number548000
Brand Family Calbiochem®
SynonymsAPDC, Ammonium Pyrrolidinedithiocarbamate, PDTC, NH₄
References
ReferencesTsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.
Pan, Z., et al. 1995. J. Biol. Chem. 270, 7787.
Bessho, R., et al. 1994. Biochem. Pharmacol. 48, 1883.
Sherman, M.P., et al. 1993. Biochem. Biophys. Res. Commun. 191, 1301.
Schreck, R., et al. 1992. J. Exp. Med. 175, 1181.
Product Information
CAS number5108-96-3
ATP CompetitiveN
FormWhite solid
Hill FormulaC₅H₁₂N₂S₂
Chemical formulaC₅H₁₂N₂S₂
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetInduction of nitric oxide synthase activity in rat alveolar macrophages
Purity≥98% by titration
Physicochemical Information
Cell permeableY
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +2°C to +8°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 3 months at -20°C.



From Catalog:
Desc. Field- added "cell-permeable
Global Trade Item Number
Catalogue Number GTIN
548000-100MGCN 07790788051419