548000 Sigma-Aldrich1-Pyrrolidinecarbodithioic Acid, Ammonium Salt - CAS 5108-96-3 - Calbiochem
Cell permeable. Inhibits the induction of NOS activity in rat alveolar macrophages. Prevents apoptosis in human HL-60 cells and thymocytes, but induces apoptosis in human and rat smooth muscle cells.
More>> Cell permeable. Inhibits the induction of NOS activity in rat alveolar macrophages. Prevents apoptosis in human HL-60 cells and thymocytes, but induces apoptosis in human and rat smooth muscle cells. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: APDC, Ammonium Pyrrolidinedithiocarbamate, PDTC, NH₄
Recommended Products
Overview
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Key Spec Table
| CAS # | Empirical Formula |
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| 5108-96-3 | C₅H₁₂N₂S₂ |
Products
| Catalogue Number | Packaging | Qty/Pack | |
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| 548000-100MGCN | Plastic ampoule | 100 mg |
| Product Information | |
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| CAS number | 5108-96-3 |
| ATP Competitive | N |
| Form | White solid |
| Hill Formula | C₅H₁₂N₂S₂ |
| Chemical formula | C₅H₁₂N₂S₂ |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | Induction of nitric oxide synthase activity in rat alveolar macrophages |
| Purity | ≥98% by titration |
| Physicochemical Information | |
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| Cell permeable | Y |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 548000-100MGCN | 07790788051419 |
Documentation
1-Pyrrolidinecarbodithioic Acid, Ammonium Salt - CAS 5108-96-3 - Calbiochem SDS
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1-Pyrrolidinecarbodithioic Acid, Ammonium Salt - CAS 5108-96-3 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 548000 |
References
| Reference overview |
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| Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667. Pan, Z., et al. 1995. J. Biol. Chem. 270, 7787. Bessho, R., et al. 1994. Biochem. Pharmacol. 48, 1883. Sherman, M.P., et al. 1993. Biochem. Biophys. Res. Commun. 191, 1301. Schreck, R., et al. 1992. J. Exp. Med. 175, 1181. |
Brochure
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| Caspases and other Apoptosis Related Tools Brochure |
| Pathways and Biomarkers of Oxidative Stress |
Citations
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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