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420134 JNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable - Calbiochem

The JNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.

Sinónimos: H₂N-YGRKKRRQRRR-RPKRPTTLNLF-NH₂, TAT₃₈₋₄₈ -Truncated Inhibitor based on JNK-Interacting Protein 1

Primary Target: JNK
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420134
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Descripción

Replacement Information

Tabla espec. clave

Empirical Formula
C₁₂₅H₂₂₀N₅₂O₂₇

Precios y disponibilidad

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420134-2MG
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      Description
      OverviewThe non-permeant JNK inhibitor peptide TI-JIP153-163 (Cat. No. 420133) is made cell-permeable with an N-terminal TAT protein transduction domain sequence. Shown to offer neuroprotection in a rat ischemic brain injury model in in vivo.
      Catalogue Number420134
      Brand Family Calbiochem®
      SynonymsH₂N-YGRKKRRQRRR-RPKRPTTLNLF-NH₂, TAT₃₈₋₄₈ -Truncated Inhibitor based on JNK-Interacting Protein 1
      References
      ReferencesGuan, Q.H., et al. 2006. Neuroscience, 139, 609.
      Barr, R.K., et al. 2004. J. Biol. Chem. 279, 36327.
      Bogoyevitch, M.A., et al. 2003. Cell. Mol. Biol. Lett. 8, 550.
      Barr, R.K., et al. 2002. J. Biol. Chem. 277, 10987.
      Product Information
      ATP CompetitiveN
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₁₂₅H₂₂₀N₅₂O₂₇
      Chemical formulaC₁₂₅H₂₂₀N₅₂O₂₇
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetJNK
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceH-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Arg-Pro-Lys-Arg-Pro-Thr-Thr-Leu-Asn-Leu-Phe-NH₂
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      420134-2MG 04055977187649

      Documentation

      JNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable - Calbiochem Ficha datos de seguridad (MSDS)

      Título

      Ficha técnica de seguridad del material (MSDS) 

      JNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable - Calbiochem Certificados de análisis

      CargoNúmero de lote
      420134

      Referencias bibliográficas

      Visión general referencias
      Guan, Q.H., et al. 2006. Neuroscience, 139, 609.
      Barr, R.K., et al. 2004. J. Biol. Chem. 279, 36327.
      Bogoyevitch, M.A., et al. 2003. Cell. Mol. Biol. Lett. 8, 550.
      Barr, R.K., et al. 2002. J. Biol. Chem. 277, 10987.
      Ficha técnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision25-July-2008 RFH
      SynonymsH₂N-YGRKKRRQRRR-RPKRPTTLNLF-NH₂, TAT₃₈₋₄₈ -Truncated Inhibitor based on JNK-Interacting Protein 1
      DescriptionThe non-permeant JNK inhibitor peptide TI-JIP153-163 (Cat. No. 420133) is made cell-permeable with an N-terminal TAT protein transduction domain sequence. Shown to offer neuroprotection in a rat ischemic brain injury model in in vivo.
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₁₂₅H₂₂₀N₅₂O₂₇
      Peptide SequenceH-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Arg-Pro-Lys-Arg-Pro-Thr-Thr-Leu-Asn-Leu-Phe-NH₂
      Purity≥97% by HPLC
      SolubilityDMSO (5 mg/ml) or H₂O (1 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesGuan, Q.H., et al. 2006. Neuroscience, 139, 609.
      Barr, R.K., et al. 2004. J. Biol. Chem. 279, 36327.
      Bogoyevitch, M.A., et al. 2003. Cell. Mol. Biol. Lett. 8, 550.
      Barr, R.K., et al. 2002. J. Biol. Chem. 277, 10987.