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178220 Antipain, Hydrochloride - CAS 37682-72-7 - Calbiochem

Antipain, Hydrochloride, CAS 37682-72-7, is a peptidyl arginine aldehyde protease inhibitor of trypsin-like serine proteases, papain, and some cysteine proteases (IC50 = 300 µM).

Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Primary Target: Trypsin-like serine proteases
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178220
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Replacement Information

Tabla espec. clave

CAS #Empirical Formula
37682-72-7C₂₇H₄₄N₁₀O₆ · HCl

Precios y disponibilidad

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178220-10MG
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      		 Ampolla de plást. 10 mg
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      178220-5MG
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          		 Frasco de vidrio 5 mg
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          Description
          OverviewPeptidyl arginine aldehyde protease inhibitor produced by actinomycetes. Inhibitor of Ca2+-dependent endopeptidases. Has specificity similar to Leupeptin (Cat. No. 108975). Inhibits trypsin-like serine proteases, papain and some cysteine proteases (IC50 = 300 µM).
          Effective concentration: 1-100 µM.
          Catalogue Number178220
          Brand Family Calbiochem®
          References
          ReferencesLyupina, Y.V., et al. 1996. Eur. J. Pharmacol. 304, 23.
          Umezawa, H. 1976. Methods Enzymol. 55, 678.
          Product Information
          CAS number37682-72-7
          ATP CompetitiveN
          FormWhite or slightly yellowish solid
          Hill FormulaC₂₇H₄₄N₁₀O₆ · HCl
          Chemical formulaC₂₇H₄₄N₁₀O₆ · HCl
          Hygroscopic Hygroscopic
          ReversibleN
          Quality LevelMQ100
          Applications
          ApplicationAntipain, Hydrochloride, CAS 37682-72-7, is a peptidyl arginine aldehyde protease inhibitor of trypsin-like serine proteases, papain, and some cysteine proteases (IC50 = 300 µM).
          Biological Information
          Primary TargetTrypsin-like serine proteases
          Primary Target IC<sub>50</sub>300 µM against trypsin-like serine proteases, papain and some cysteine proteases
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSYV9350800
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Número de referencia GTIN
          178220-10MG 04055977223088
          178220-5MG 04055977223095

          Documentation

          Antipain, Hydrochloride - CAS 37682-72-7 - Calbiochem Ficha datos de seguridad (MSDS)

          Título

          Ficha técnica de seguridad del material (MSDS) 

          Antipain, Hydrochloride - CAS 37682-72-7 - Calbiochem Certificados de análisis

          CargoNúmero de lote
          178220

          Referencias bibliográficas

          Visión general referencias
          Lyupina, Y.V., et al. 1996. Eur. J. Pharmacol. 304, 23.
          Umezawa, H. 1976. Methods Enzymol. 55, 678.
          Ficha técnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision26-September-2007 RFH
          DescriptionPeptidyl arginine aldehyde protease inhibitor produced by actinomycetes. Inhibitor of Ca2+-dependent endopeptidases. Has specificity similar to Leupeptin (Cat. No. 108975). Inhibits trypsin-like serine proteases, papain, and some cysteine proteases (IC50 ~500 ng/ml). Effective at concentrations of 1-100 µM.
          FormWhite or slightly yellowish solid
          CAS number37682-72-7
          RTECSYV9350800
          Chemical formulaC₂₇H₄₄N₁₀O₆ · HCl
          SolubilityH₂O (10 mg/ml)
          Storage +2°C to +8°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.
          Toxicity Standard Handling
          ReferencesLyupina, Y.V., et al. 1996. Eur. J. Pharmacol. 304, 23.
          Umezawa, H. 1976. Methods Enzymol. 55, 678.