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  • Sodium-level-sensitive sodium channel Na(x) is expressed in glial laminate processes in the sensory circumventricular organs. 16223844

    Na(x) is an atypical sodium channel that is assumed to be a descendant of the voltage-gated sodium channel family. Our recent studies on the Na(x)-gene-targeting mouse revealed that Na(x) channel is localized to the circumventricular organs (CVOs), the central loci for the salt and water homeostasis in mammals, where the Na(x) c...
    Document Type:
    Reference
    Product Catalog Number:
    AP183P
    Product Catalog Name:
    Goat Anti-Rat IgG Antibody, HRP conjugate, Species Adsorbed

  • Astrocyte IP3R2-dependent Ca(2+) signaling is not a major modulator of neuronal pathways governing behavior. 25429263

    Calcium-dependent release of gliotransmitters by astrocytes is reported to play a critical role in synaptic transmission and be necessary for long-term potentiation (LTP), long-term depression (LTD) and other forms of synaptic modulation that are correlates of learning and memory. Further, physiological processes reported to be...
    Document Type:
    Reference
    Product Catalog Number:
    AB3000
    Product Catalog Name:
    Anti-IP3 Receptor Type II Antibody

  • 3-D neurohistology of transparent tongue in health and injury with optical clearing. 24155698

    Tongue receives extensive innervation to perform taste, sensory, and motor functions. Details of the tongue neuroanatomy and its plasticity in response to injury offer insights to investigate tongue neurophysiology and pathophysiology. However, due to the dispersed nature of the neural network, standard histology cannot provide...
    Document Type:
    Reference
    Product Catalog Number:
    AB152
    Product Catalog Name:
    Anti-Tyrosine Hydroxylase Antibody

  • The dorsal raphe modulates sensory responsiveness during arousal in zebrafish. 23100441

    During waking behavior, animals adapt their state of arousal in response to environmental pressures. Sensory processing is regulated in aroused states, and several lines of evidence imply that this is mediated at least partly by the serotonergic system. However, there is little information directly showing that serotonergic func...
    Document Type:
    Reference
    Product Catalog Number:
    MAB352
    Product Catalog Name:
    Anti-Serotonin Antibody, clone YC5/45

  • Sodium depletion activates the aldosterone-sensitive neurons in the NTS independently of thirst. 17068161

    Thirst and sodium appetite are both critical for restoring blood volume. Because these two behavioral drives can arise under similar physiological conditions, some of the brain sensory sites that stimulate thirst may also drive sodium appetite. However, the physiological and temporal dynamics of these two appetites exhibit clear...
    Document Type:
    Reference
    Product Catalog Number:
    AB1542
    Product Catalog Name:
    Anti-Tyrosine Hydroxylase Antibody

  • Neural correlates of water reward in thirsty Drosophila. 25262493

    Drinking water is innately rewarding to thirsty animals. In addition, the consumed value can be assigned to behavioral actions and predictive sensory cues by associative learning. Here we show that thirst converts water avoidance into water-seeking in naive Drosophila melanogaster. Thirst also permitted flies to learn olfactory...
    Document Type:
    Reference
    Product Catalog Number:
    AB152
    Product Catalog Name:
    Anti-Tyrosine Hydroxylase Antibody

  • Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson\'s disease. 21517843

    Wilson\'s disease (WD) is caused by mutations in the copper transporting ATPase 7B (Atp7b). Patients present with liver pathology or behavioural disturbances. Studies on rodent models for WD so far mainly focussed on liver, not brain. The effect of knockout of atp7b on sensori-motor and cognitive behaviour, as well as neuronal n...
    Document Type:
    Reference
    Product Catalog Number:
    MAB5572
    Product Catalog Name:
    Anti-NMDAR2A Antibody

  • Long-term preservation of cone photoreceptors and visual acuity in rd10 mutant mice exposed to continuous environmental enrichment. 25489227

    In human patients and animal models of retinitis pigmentosa (RP), a gradual loss of rod photoreceptors and decline in scotopic vision are the primary manifestations of the disease. Secondary death of cones and gradual, regressive remodeling of the inner retina follow and progress at different speeds according to the underlying g...
    Document Type:
    Reference
    Product Catalog Number:
    Multiple
    Product Catalog Name:
    Multiple