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65035 Trypsin Inhibitor, Soybean - CAS 9035-81-8 - Calbiochem

Trypsin Inhibitor, Soybean, CAS 9035-81-8, is a reversible inhibitor of trypsin that binds to trypsin in a stoichiometric, pH-dependent manner (Kd = 500 nM at pH 7.8).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: trypsin
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65035
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Overview

Replacement Information

Key Spec Table

CAS #
9035-81-8

Pricing & Availability

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65035-100MG
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      		 Plastic ampoule 100 mg
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      Description
      OverviewA reversible inhibitor of trypsin that binds to trypsin in a stoichiometric, pH-dependent manner (Kd = 500 nM at pH 7.8).
      Catalogue Number65035
      Brand Family Calbiochem®
      References
      ReferencesLilly, C.M., et al. 1993. J. Clin. Invest. 91, 235.
      Uchino, T., et al. 1993. J. Biol. Chem. 268, 527.
      Birk, Y. 1976. Methods Enyzmol. 45, 700.
      Product Information
      CAS number9035-81-8
      Unit of DefinitionOne unit is defined as the amount of protein that will inhibit 1 unit of trypsin activity using BAEE as a substrate at 25°C, pH 7.6.
      ATP CompetitiveN
      FormOff-white lyophilized solid
      Hygroscopic Hygroscopic
      ReversibleY
      Quality LevelMQ100
      Applications
      ApplicationTrypsin Inhibitor, Soybean, CAS 9035-81-8, is a reversible inhibitor of trypsin that binds to trypsin in a stoichiometric, pH-dependent manner (Kd = 500 nM at pH 7.8).
      Biological Information
      Primary Targettrypsin
      Primary Target IC<sub>50</sub>Kd = 500 nM at pH 7.8 against trypsin
      Specific Activity≥4000 units/mg protein
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Moisture Protect from moisture
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 week at 4°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      65035-100MG 07790788052164

      Documentation

      Trypsin Inhibitor, Soybean - CAS 9035-81-8 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Trypsin Inhibitor, Soybean - CAS 9035-81-8 - Calbiochem Certificates of Analysis

      TitleLot Number
      65035

      References

      Reference overview
      Lilly, C.M., et al. 1993. J. Clin. Invest. 91, 235.
      Uchino, T., et al. 1993. J. Biol. Chem. 268, 527.
      Birk, Y. 1976. Methods Enyzmol. 45, 700.

      Citations

      Title
    • Elizabeth A. Lipscomb, et al. (2005) The α6β4 integrin maintains the survival of human breast carcinoma cells in vivo. Cancer Research 65, 10970-10976.
      		•
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision02-October-2017 JSW
      DescriptionReversible inhibitor of trypsin that binds to trypsin in a stoichiometric, reversible and pH-dependent manner (Kd = 0.5 nM at pH 7.8). Also inhibits, to a lesser degree, chymotrypsin, kallikrein, plasmin, and other serine proteases.
      FormOff-white lyophilized solid
      Recommended reaction conditionsInactivates trypsin on an equal molar basis. To ensure complete inhibition of trypsin activity, a working concentration of soybean trypsin inhibitor should exceed that of trypsin by a factor of at least 2.
      CAS number9035-81-8
      Specific activity≥4000 units/mg protein
      Unit definitionOne unit is defined as the amount of protein that will inhibit 1 unit of trypsin activity using BAEE as a substrate at 25°C, pH 7.6.
      Solubility67 mM potassium phosphate, pH 7.6 (5 mg/ml)
      Storage Protect from moisture
      -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 week at 4°C.
      Toxicity Standard Handling
      ReferencesLilly, C.M., et al. 1993. J. Clin. Invest. 91, 235.
      Uchino, T., et al. 1993. J. Biol. Chem. 268, 527.
      Birk, Y. 1976. Methods Enyzmol. 45, 700.
      Citation
    • Elizabeth A. Lipscomb, et al. (2005) The α6β4 integrin maintains the survival of human breast carcinoma cells in vivo. Cancer Research 65, 10970-10976.
      		•