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108386 Tris(hydroxymethyl)aminomethane

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
77-86-1201-064-4C₄H₁₁NO₃H₂NC(CH₂OH)₃121.14 g/molPh Eur,BP,ChP,JPC,USP

Pricing & Availability

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1083861000
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      Plastic bottle 1 kg
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      1083869025
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          25 kg
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          Description
          Catalogue Number108386
          SynonymsTrometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer
          DescriptionTris(hydroxymethyl)aminomethane
          References
          Product Information
          CAS number77-86-1
          EC number201-064-4
          GradePh Eur,BP,ChP,JPC,USP
          Hill FormulaC₄H₁₁NO₃
          Chemical formulaH₂NC(CH₂OH)₃
          Molar Mass121.14 g/mol
          HS Code2922 19 99
          Structure formula ImageStructure formula Image
          Quality LevelMQ500
          Applications
          Biological Information
          Physicochemical Information
          Boiling point219 - 220 °C (13.3 hPa)
          Density1.32 g/cm3 (20 °C)
          Melting Point169 °C
          pH value10.2 - 10.6 (6 g/l, H₂O, 20 °C)
          Vapor pressure<0.1 hPa (20 °C)
          Bulk density840 kg/m3
          Solubility678 g/l
          Dimensions
          Materials Information
          Toxicological Information
          LD 50 oralLD50 Rat > 5000 mg/kg
          LD 50 dermalLD50 Rat > 5000 mg/kg
          Safety Information according to GHS
          RTECSTY2900000
          Storage class10 - 13 Other liquids and solids
          WGKWGK 1 slightly hazardous to water
          Disposal3
          Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          StorageNoTempLimit
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalogue Number GTIN
          1083861000 04022536103846
          1083869025 04022536103853

          Documentation

          Material Qualification Dossier

          TitleVersion
          6.0

          Quality Management Dossier (Open Access)

          Title

          Operational Excellence Dossier

          Title

          Tris(hydroxymethyl)aminomethane SDS

          Title

          Safety Data Sheet (SDS) 

          Tris(hydroxymethyl)aminomethane Certificates of Analysis

          Product Number PackagingSpecificationLot Number
          1083861000 Plastic bottlePDF Specification Document
          1083869025 PDF Specification Document

          Certificates

          Title

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          Categories

          Biopharmaceutical Manufacturing > Downstream Processing > Chromatography > Process Chemicals > Buffers
          Small Molecule Pharmaceuticals > Formulation > Semisolid Dosage Form > Acidulants and pH Adjustments
          Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > pH Adjustments and Isotonizers
          Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > pH Adjustments and Isotonizers