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MAIPN4550 MultiScreen-IP Filter Plate, 0.45 µm, clear, non-sterile

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MAIPN4550
50  
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      Overview

      Description
      Catalogue NumberMAIPN4550
      Trade Name
      • MultiScreen
      DescriptionMultiScreen-IP Filter Plate, 0.45 µm, clear, non-sterile
      Background InformationIncreasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates.

      MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.

      Membranes have uniform pore structure and density for reliable transport:
      - Individual wells minimize candidate cross-talk
      - Compatibility with automated liquid handling systems increases throughput

      Permeability Assay:
      - The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1

      PAMPA Assay:
      - The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3

      MultiScreen Acceptor Plate:
      - The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.
      Product Information
      Automation CompatibleNo
      Filter CodeIP
      Color CodeClear
      Number of Wells96
      Quality LevelMQ400
      Applications
      ApplicationNon-sterile, clear 96-well filter plate with 0.45 um pore size Hydrophobic PVDF membrane for Avidin-biotin Linkages, DNA-binding Proteins, Protein Binding & PAMPA. Comes in a pack of 50.
      Key Applications
      • Avidin-biotin Linkages
      • DNA-binding Proteins
      • Protein Binding
      • PAMPA
      Biological Information
      MediaImmobilon®-P
      SterilityNon-Sterile
      Physicochemical Information
      Pore Size0.45 µm
      Dimensions
      Filtration Area0.3cm2
      Volume50 µL–250 µL
      Materials Information
      Chemistry
      • Hydrophobic Polyvinylidene Fluoride (PVDF)
      Device Material
      • Acrylic
      Packaging Information
      Material Size50
      Global Trade Item Number
      Catalogue Number GTIN
      MAIPN4550 04053252361296