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HUMU-210K MILLIPLEX® Humanized Mouse Panel

MILLIPLEX® Qualified assays undergo rigourous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 41 analytes in humanized mouse s

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HUMU-210K

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Overview

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This panel is available for custom premix. Talk to your Protein Specialist today!
Description
Catalogue NumberHUMU-210K
Trade Name
  • MILLIPLEX
DescriptionMILLIPLEX® Humanized Mouse Panel
OverviewMILLIPLEX® kits offer the broadest selection of analytes across a wide range of disease states and species. Once the analytes of interest have been identified, you can rely on the quality that we build into each kit to produce results you can trust. In addition to the assay characteristics listed in the protocol, other performance criteria evaluated during the verification process include cross-reactivity, dilution linearity, kit stability, and sample behavior (e.g. detectability and stability).

Each MILLIPLEX® kit includes:
• Quality controls (QCs) to qualify assay performance
• Comparison of standard (calibrator) and QC lots to a reference lot to ensure lot-to-lot consistency
• Detection antibody cocktails designed to yield consistent analyte profiles within panel

In addition, each panel and kit meet stringent manufacturing criteria to ensure batch to-batch reproducibility. MILLIPLEX® Humanized Mouse Panel is part of the most versatile system available for research in humanized mouse models. From our single to multiplex biomarker solutions, we partner with you to design, develop, analytically verify, and build the most comprehensive library available for protein detection and quantitation.
Background InformationHumanized mouse research has emerged as a pivotal tool in biomedical science, bridging the gap between preclinical studies and human disease. By engrafting human tissues, cells, or genes into immunocompromised mice, researchers can create models that more accurately mimic human immune responses and disease mechanisms. This innovative approach enhances the relevance of immunoassays, which are critical for evaluating immune function, disease progression, and therapeutic efficacy. As the demand for more predictive models in drug development and disease research grows, humanized mice are proving invaluable for advancing our understanding of human biology and improving therapeutic strategies.
Product Information
Detection methodLuminex xMAP
ConfigurationDesign your multiplex kit by choosing available analytes within this panel.
Precision, %
  • Intra-assay: <15%
  • Inter-assay: <20%
Panel TypeMAGNETIC Circulating Cancer
Quality LevelMQ200
Applications
ApplicationMILLIPLEX® Qualified assays undergo rigourous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 41 analytes in humanized mouse serum, plasma, and cell culture supernatants.
Key Applications
  • Multiplexing
Application Notes• This is an overnight assay.
• This assay requires 10 µL of plasma, serum, or cell culture supernatant per well.
• This kit may be used for the analysis of any or all of the Humanized Mouse analytes in humanized mouse cell lysate and culture supernatant samples and serum or plasma samples.
Biological Information
Species Reactivity
  • Human
  • Mouse
Analytes Available
  • G-CSF
  • GM-CSF
  • IFNγ
  • IL-1α
  • IL-1β
  • IL-2
  • IL-3
  • IL-4
  • IL-5
  • IL-6
  • IL-7
  • IL-8
  • IL-12 (p40)
  • IL-12 (p70)
  • IL-15
  • IL-17A
  • IL-18
  • IP-10
  • M-CSF
  • MIG
  • TNFα
  • MCP-1/CCL2
Cross ReactivityRefer to kit protocol for cross-reactivity statement.
Accuracy
  • 87% - 99%
Physicochemical Information
Sensitivity
  • Refer to kit protocol for sensitivities for individual cytokines, chemokines and growth factors.
Standard Curve Range
  • Refer to kit protocol for standard curve ranges for individual analytes.
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsRecommended storage for kit components is 2 - 8°C.
Packaging Information
Material Size96-well plate
Material Package96 well plate
Global Trade Item Number
Catalogue Number GTIN
HUMU-210K 04065272127363