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101544 L-Arginine monohydrochloride

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
1119-34-2214-275-1C₆H₁₄N₄O₂˙ ClHC₆H₁₄N₄O₂*HCl210.67 g/molPh Eur,BP,ChP,JP,USP

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      Plastic drum 10 kg
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      Description
      Catalogue Number101544
      Synonymsa-Amino-d-guanidino valerianic acid hydrochloride, alpha-Amino-delta-guanidino valerianic acid hydrochloride, Arg, α-Amino-δ-guanidino valerianic acid hydrochloride
      DescriptionL-Arginine monohydrochloride
      References
      Product Information
      CAS number1119-34-2
      EC number214-275-1
      GradePh Eur,BP,ChP,JP,USP
      Hill FormulaC₆H₁₄N₄O₂˙ ClH
      Chemical formulaC₆H₁₄N₄O₂*HCl
      Molar Mass210.67 g/mol
      HS Code2925 29 19
      Structure formula ImageStructure formula Image
      Quality LevelMQ500
      Applications
      Biological Information
      Physicochemical Information
      Density1.42 g/cm3 (20 °C)
      Melting Point>235 °C
      pH value5.5 - 7 (211 g/l, H₂O, 25 °C)
      Vapor pressure<0.1 Pa (20 °C)
      Bulk density1250 kg/m3
      Solubility730 g/l
      Dimensions
      Materials Information
      Toxicological Information
      LD 50 oralLD50 Rat 12000 mg/kg
      Safety Information according to GHS
      RTECSCF1995500
      Storage class10 - 13 Other liquids and solids
      WGKWGK 1 slightly hazardous to water
      Disposal3
      Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at +2°C to +30°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Assay (perchloric acid titration, calculated on dried substance)98.5 - 101.0 %
      Identity (IR-spectrum)passes test
      Identity (wet chemistry)passes test
      Identity (specific rotation)passes test
      Identity (TLC)passes test
      Appearancewhite to almost white or colorless, irregular crystals
      Appearance of solution (50 g/l; water)clear and not more intense in color than reference solution BY₆
      Appearance of solution (100 g/l, water)clear and colorless
      Transmittance of solution (100 g/l, water)≥ 98.0 %
      pH (100 g/l, CO₂-free water)4.7 - 6.2
      Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 250 g/l, calc. on dried substance)+21.0 to +23.5
      Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance)+21.5 to +23.5
      Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 6 mol/l,previously dried substance)+21.5 to +23.5
      Chloride (Cl) (argentometric)16.5 - 17.1 %
      Chloride (argentometric, calc. on dried substance)16.5 - 17.1 %
      Proteinspasses test
      Sulfate (SO₄)≤ 200 ppm
      Phosphate (PO43-)≤ 200 ppm
      Heavy metals (as Pb)≤ 10 ppm
      As (Arsenic)≤ 1 ppm
      Fe (Iron)≤ 10 ppm
      Other amino acids (TLC)≤ 0.2 %
      Related Compounds, total (TLC)≤ 0.5 %
      Related substances (TLC)passes test
      Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.2 %
      Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
      Ninhydrin-positive substances (LC) (total impurities)≤ 0.5 %
      Residual solvents (ICH Q3C)excluded by manufacturing process
      Sulfated ash (600 °C)≤ 0.1 %
      Loss on drying (105 °C, 2 h)≤ 0.20 %
      Bacterial endotoxins≤ 3.0 I.U./g
      Bacterial endotoxins (ChP)≤ 3.0 I.U./g
      Microbiological test (total aerobic microbial count (TAMC))≤ 10²
      Microbiological test (total yeast and mould count (TYMC))≤ 10¹
      Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
      Compliance with pyrogens (according to ChP) is guaranteed by the test for bacterial endotoxins (ChP) and the production process.
      Corresponds to Ph. Eur., BP, ChP, JP, USP.
      Global Trade Item Number
      Catalogue Number GTIN
      1015449010 04022536706757

      Documentation

      Material Qualification Dossier

      TitleVersion
      10.0

      Quality Management Dossier (Open Access)

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      Operational Excellence Dossier

      Title

      L-Arginine monohydrochloride SDS

      Title

      Safety Data Sheet (SDS) 

      L-Arginine monohydrochloride Certificates of Analysis

      Product Number PackagingSpecificationLot Number
      1015449010 Plastic drumPDF Specification Document

      Certificates

      Title