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368020 Gramicidin A, High Purity, Bacillus brevis - CAS 11029-61-1 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
11029-61-1C₉₉H₁₄₀N₂₀O₁₇

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368020-25MG
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      Plastic ampoule 25 mg
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      Description
      OverviewNaturally-occurring ion channel-forming pentadecapeptide. The association of two gA peptides causes the formation of a monovalent cation-selective ion channel. Causes K+/H+ exchange in mitochondria in a non-voltage dependent manner. Causes red blood cell lysis at 0.5-1.0 µg/ml.
      Catalogue Number368020
      Brand Family Calbiochem®
      SynonymsgA
      References
      ReferencesQuigley, E.P., et al. 2000. J. Membr. Biol. 174, 207.
      Koeppe, R.E., et al. 1995. Biochemistry 34, 9299.
      Ketchem, R.R., et al. 1993. Science 261, 1457.
      Stankovic, C.J., et al. 1990. Anal. Biochem. 184, 100.
      Product Information
      CAS number11029-61-1
      ATP CompetitiveN
      FormWhite to off-white solid
      Hill FormulaC₉₉H₁₄₀N₂₀O₁₇
      Chemical formulaC₉₉H₁₄₀N₂₀O₁₇
      ReversibleN
      Quality LevelMQ100
      Biological Information
      Primary TargetCauses the formation of a monovalent cation-selective ion channel
      Purity≥90% by HPLC
      Physicochemical Information
      Cell permeableN
      ContaminantsgC isomers: < 5% by HPLC
      Peptide SequenceHCO-Val-Gly-Ala-D-Leu-Ala-D-Val-Val-D-Val-Trp-D-Leu-Trp-D-Leu-Trp-D-Leu-Trp-NHCH₂CH₂OH
      Safety Information according to GHS
      RTECSMD8230000
      Safety Information
      R PhraseR: 20/21/22-36/37/38

      Harmful by inhalation, in contact with skin and if swallowed.
      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing recosntituion, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      368020-25MG 04055977192094