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The following MAPmates™ should not be plexed together:
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48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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208722
Sigma-AldrichCalpain Inhibitor III - CAS 88191-84-8 - Calbiochem
Calpain Inhibitor III, CAS 88191-84-8, is a potent, cell-permeable inhibitor of calpain I and II (Ki = 8 nM).
More>>Calpain Inhibitor III, CAS 88191-84-8, is a potent, cell-permeable inhibitor of calpain I and II (Ki = 8 nM). Less<<
MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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Description
Overview
A potent, cell-permeable inhibitor of calpain I and II (Ki = 8 nM). Reduces capsaicin-mediated cell death in cultured dorsal root ganglion. Reported to block A23187-induced suppression of neurite outgrowth in isolated hippocampal pyramidal neurons. Exhibits neuroprotective effect in glutamate-induced toxicity.
Catalogue Number
208722
Brand Family
Calbiochem®
Synonyms
Carbobenzoxy-valinyl-phenylalaninal, MDL 28170
References
References
Chatterjee, S., et al. 1998. J. Med. Chem.41, 2663. Rami, A., et al. 1997. Neurosci. Res. 27, 93. Yamazaki, T., et al. 1997. Biochemistry36, 8377. Klafki, H., et al. 1996. J. Biol. Chem.271, 28655. Chard, P.S., et al. 1995. Neuroscience 65, 1099. Song, D.K., et al. 1994. J. Neurosci. Res. 39, 474.
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
28-May-2008 RFH
Synonyms
Carbobenzoxy-valinyl-phenylalaninal, MDL 28170
Description
A potent, cell-permeable inhibitor of calpain I and II (Ki = 8 nM) that also reduces capsaicin-mediated cell death in cultured dorsal root ganglion. Reported to block A23187-induced suppression of neurite outgrowth in isolated hippocampal pyramidal neurons. Exhibits neuroprotective effects against glutamate-induced toxicity.
Form
White lyophilized solid
CAS number
88191-84-8
Chemical formula
C₂₂H₂₆N₂O₄
Peptide Sequence
Z-Val-Phe-CHO
Structure formula
Purity
≥95% by HPLC
Solubility
DMSO (20 mg/ml). Use only anhydrous DMSO.
Storage
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Toxicity
Standard Handling
References
Chatterjee, S., et al. 1998. J. Med. Chem.41, 2663. Rami, A., et al. 1997. Neurosci. Res. 27, 93. Yamazaki, T., et al. 1997. Biochemistry36, 8377. Klafki, H., et al. 1996. J. Biol. Chem.271, 28655. Chard, P.S., et al. 1995. Neuroscience 65, 1099. Song, D.K., et al. 1994. J. Neurosci. Res. 39, 474.
