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Amyloid Precursor Protein Antibodies

APP is the precursor molecule whose proteolysis generates beta amyloid (Aβ), a 37 to 49 amino acid peptide that is the primary component of amyloid plaques found in Alzheimer's disease patients.

Overview

Specifications

Ordering Information

Amyloid Precursor Protein AntibodiesClear Sorting & Filtering Show Filter
Catalogue NumberDescriptionImmunogenHostKey ApplicationsSpecificitySpecies Reactivity
MAB348Anti-APP A4 Antibody, a.a. 66-81 of APP {NT}, clone 22C11 Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein. Mouse Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blotting Reacts with pre-A4. The antibody recognizes amino acids 66-81 of the N-terminus on the pre-A4 molecule (Hilbich et al., 1993). 22C11 recognizes all three isoforms of APP, immature ~110kDa, sAPP ~120kDa, and mature ~130kDa (Hoffmann et al., 2000). The antibody is known to cross react with APLP2 (Slunt, 1994). Canine, Human, Mouse, Monkey, Pig, Rat, Fish Show Pricing & Availability
MAB348-100ULAnti-APP A4 Antibody, a.a. 66-81 of APP (NT), clone 22C11 Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein. Mouse Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blotting Reacts with pre-A4. The antibody recognizes a N-terminal epitope on the pre-A4 molecule Human, Mouse, Rat, Monkey, Pig, Fish Show Pricing & Availability
MAB5354Anti-Amyloid β Precursor Protein Antibody, KPI domain, clone 4.1 Purified recombinant KPI domain of Amyloid-beta precursor protein. Mouse ELISA, Western Blotting, Immunohistochemistry Amyloid-beta Precursor Protein, KPI (Kunitz protease inhibitor) domain. The antibody reacts with both native and recombinant protein. The antibody has been shown to partially inhibit protease inhibitory properties. Human Show Pricing & Availability

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