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407306 γ-Interferon, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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407306
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Overview

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407306-100UG
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      		 Plastic ampoule 100 μg
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      Description
      OverviewRecombinant, human γ-interferon expressed in E. coli. A multi-functional protein consisting of 144 amino acids. Exhibits antiviral and antitumor properties. Regulates the development of specific immune responses.
      Catalogue Number407306
      Brand Family Calbiochem®
      References
      ReferencesKohji, K., et al. 1994. J. Int. J. Cancer 58, 380.
      Kolb, J.P., et al. 1994. J. Biol. Chem. 269, 9811.
      Müller, U., et al. 1994. Science 264, 1918.
      Zahedi, K., et al. 1994. J. Biol. Chem. 269, 9669.
      Shuai, K., et al. 1993. Science 261, 1744.
      Wilson, K.C., and Finbloom, D.S. 1992. Proc. Natl. Acad. Sci. USA 89, 11964.
      Meager, A. 1987. Lymphokines and Interferons, A Practical Approach (Clemens, M.J., et al., eds.) p. 129, IRL Press, Oxford.
      Product Information
      FormLiquid
      FormulationSterile-filtered (0.22 µm) in 40 mM Tris-HCl, pH 7.4, carrier-free.
      Quality LevelMQ100
      Applications
      Biological Information
      Biological activityED₅₀ = 0.5-3.0 ng/ml as measured by inhibition (cytostasis) of human WiDr cells.
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Do not store in glass vials without addition of carrier protein. Further dilute in low endotoxin medium or buffer containing FBS or tissue culture grade BSA.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      407306-100UG 04055977188257

      Documentation

      γ-Interferon, Human, Recombinant, E. coli SDS

      Title

      Safety Data Sheet (SDS) 

      γ-Interferon, Human, Recombinant, E. coli Certificates of Analysis

      TitleLot Number
      407306

      References

      Reference overview
      Kohji, K., et al. 1994. J. Int. J. Cancer 58, 380.
      Kolb, J.P., et al. 1994. J. Biol. Chem. 269, 9811.
      Müller, U., et al. 1994. Science 264, 1918.
      Zahedi, K., et al. 1994. J. Biol. Chem. 269, 9669.
      Shuai, K., et al. 1993. Science 261, 1744.
      Wilson, K.C., and Finbloom, D.S. 1992. Proc. Natl. Acad. Sci. USA 89, 11964.
      Meager, A. 1987. Lymphokines and Interferons, A Practical Approach (Clemens, M.J., et al., eds.) p. 129, IRL Press, Oxford.

      Citations

      Title
    • Sambit K. Nanda and Michael D. Baron. (2006) Rinderpest virus blocks type I and type II interferon action: role of structural and nonstructural proteins. Journal of Virology 80, 7555-7568.
    • Phuong Thi Nguyen Sarkis, et al. (2006) STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-α. Journal of Immunology 177, 4530-4540.
      		•
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-June-2008 JSW
      DescriptionRecombinant, human γ-interferon expressed in E. coli. A multi-functional protein consisting of 144 amino acids. Exhibits antiviral and antitumor properties. Regulates the development of specific immune responses. Expressed in and purified from E. coli.
      FormLiquid
      FormulationSterile-filtered (0.22 µm) in 40 mM Tris-HCl, pH 7.4, carrier-free.
      Concentration Label Please refer to vial label for lot-specific concentration
      Biological activityED₅₀ = 0.5-3.0 ng/ml as measured by inhibition (cytostasis) of human WiDr cells.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Do not store in glass vials without addition of carrier protein. Further dilute in low endotoxin medium or buffer containing FBS or tissue culture grade BSA.
      Toxicity Standard Handling
      Merck USA index14, 4992
      ReferencesKohji, K., et al. 1994. J. Int. J. Cancer 58, 380.
      Kolb, J.P., et al. 1994. J. Biol. Chem. 269, 9811.
      Müller, U., et al. 1994. Science 264, 1918.
      Zahedi, K., et al. 1994. J. Biol. Chem. 269, 9669.
      Shuai, K., et al. 1993. Science 261, 1744.
      Wilson, K.C., and Finbloom, D.S. 1992. Proc. Natl. Acad. Sci. USA 89, 11964.
      Meager, A. 1987. Lymphokines and Interferons, A Practical Approach (Clemens, M.J., et al., eds.) p. 129, IRL Press, Oxford.
      Citation
    • Sambit K. Nanda and Michael D. Baron. (2006) Rinderpest virus blocks type I and type II interferon action: role of structural and nonstructural proteins. Journal of Virology 80, 7555-7568.
    • Phuong Thi Nguyen Sarkis, et al. (2006) STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-α. Journal of Immunology 177, 4530-4540.
      		•