Millipore Sigma Vibrant Logo

567630 Sodium Salicylate - CAS 54-21-7 - Calbiochem

View Products on Sigmaaldrich.com
567630
Visualizza prezzi e disponibilità

Panoramica

Tabella delle specifiche principali

CAS #Empirical Formula
54-21-7C₇H₅O₃ · Na

Prezzi e disponibilità

Numero di catalogo DisponibilitàConfezionamento Qtà/conf Prezzo Quantità
567630-5GM
Disponibilità limitata
Disponibilità limitata
A magazzino 
Fuori produzione
Disponibili quantità limitate
La disponibilità deve essere confermata
    Prodotti rimanenti: riceverà un nostro avviso
      Prodotti rimanenti: riceverà un nostro avviso
      Will advise
      Contatti il Servizio Clienti
      Contact Customer Service

      Bottiglia di vetro 5 gm
      Non è stato possibile trovare il prezzo
      La quantità minima deve essere un multiplo di
      Maximum Quantity is
      Al termine dell'ordine Maggiori informazioni
      Lei ha salvato ()
       
      Richiedi il prezzo
      Description
      OverviewA cell-permeable, non-steroidal anti-inflammatory agent that interferes with TNF-induced NF-κB activation by inhibiting phosphorylation and subsequent degradation of the IκB-α protein. Selectively inhibits TNF-induced activation of p42 (ERK2) and p44 (ERK1) MAP kinases. Also inhibits TNF-induced activation of JNK. Induces apoptosis via p38 kinase activation. Inhibits COX-2 and inducible NOS (iNOS) transcription independently of NF-κB activation.
      Catalogue Number567630
      Brand Family Calbiochem®
      SynonymsSalicylic Acid, Na, NaSal
      References
      ReferencesSchwenger, P., et al. 1998. Mol. Cell. Biol. 18, 78.
      Mitchell, J.A., et al. 1997. Mol. Pharmacol. 51, 907.
      Schwenger, P., et al. 1997. Proc. Natl. Acad. Sci. USA 94, 2869.
      Farivar, R.S. and Brecher, P. 1996. J. Biol. Chem. 271, 31585.
      Schwenger, P., et al. 1996. J. Biol. Chem. 271, 8089.
      Product Information
      CAS number54-21-7
      ATP CompetitiveN
      FormOff-white solid
      Hill FormulaC₇H₅O₃ · Na
      Chemical formulaC₇H₅O₃ · Na
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Primary TargetTNF-induced activation of p42 (ERK2) and p44 (ERK1) MAP kinases
      Purity≥98% by titration
      Physicochemical Information
      Cell permeableY
      Safety Information according to GHS
      RTECSVO5075000
      Safety Information
      R PhraseR: 22

      Harmful if swallowed.
      S PhraseS: 24/25

      Avoid contact with skin and eyes.
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +15°C to +30°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Numero di catalogo GTIN
      567630-5GM 04055977266825