Millipore Sigma Vibrant Logo

528105 Picrotoxin, Anamirta cocculin - CAS 124-87-8 - Calbiochem

A potent antagonist of GABA receptors (IC₅₀ = 240 nM) at synapses in the central nervous system.

MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Primary Target: GABA receptors
View Products on Sigmaaldrich.com
528105
Visualizza prezzi e disponibilità

Panoramica

Replacement Information

Tabella delle specifiche principali

CAS #Empirical Formula
124-87-8C₁₅H₁₈O₇ . C₁₅H₁₆O₆

Prezzi e disponibilità

Numero di catalogo DisponibilitàConfezionamento Qtà/conf Prezzo Quantità
528105-100MG
Verifica della disponibilità in corso...
—
Disponibilità limitata Disponibilità limitata
A magazzino 
Fuori produzione
Disponibili quantità limitate
La disponibilità deve essere confermata
    Prodotti rimanenti: riceverà un nostro avviso
      Prodotti rimanenti: riceverà un nostro avviso
      Will advise
      Contatti il Servizio Clienti
      Contact Customer Service

      		 100 mg
      Ricerca del prezzo in corso...
      Non è stato possibile trovare il prezzo
      La quantità minima deve essere un multiplo di
      Maximum Quantity is
      Al termine dell'ordine Maggiori informazioni
      Lei ha salvato ()
       
      —
      Richiedi il prezzo
      		 —
      Description
      OverviewA potent antagonist of GABA receptors (IC50 = 240 nM) at synapses in the central nervous system. Inhibits 35S-TBPS binding to the Cl– channel (IC50 = 1.7 µM). Picrotoxin is a mixture of one mole of picrotoxinin and one mole of picrotin.
      Catalogue Number528105
      Brand Family Calbiochem®
      References
      ReferencesQian, H., and Dowling, J.E. 1994. J. Neurosci. 14, 4299.
      Yoon, K.W., et al. 1993. J. Physiol. 464, 423.
      Akaike, N., et al. 1985. Experientia 41, 70.
      Product Information
      CAS number124-87-8
      ATP CompetitiveN
      FormWhite to light yellow powder or crystals
      Hill FormulaC₁₅H₁₈O₇ . C₁₅H₁₆O₆
      Chemical formulaC₁₅H₁₈O₇ . C₁₅H₁₆O₆
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetGABA receptors
      Primary Target IC<sub>50</sub>240 nM against GABA receptors
      Purity≥98% (mixture of Picrotoxin and picrotin) by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSTJ9100000
      Safety Information
      R PhraseR: 26/27/28

      Very toxic by inhalation, in contact with skin and if swallowed.
      S PhraseS: 22-36/37/39-45

      Do not breathe dust.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Highly Toxic
      Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      528105-100MG 04055977270488

      Documentation

      Picrotoxin, Anamirta cocculin - CAS 124-87-8 - Calbiochem MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      Picrotoxin, Anamirta cocculin - CAS 124-87-8 - Calbiochem Certificati d'Analisi

      TitoloNumero di lotto
      528105

      Riferimenti bibliografici

      Panoramica delle referenze
      Qian, H., and Dowling, J.E. 1994. J. Neurosci. 14, 4299.
      Yoon, K.W., et al. 1993. J. Physiol. 464, 423.
      Akaike, N., et al. 1985. Experientia 41, 70.
      Scheda tecnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision15-March-2019 JSW
      DescriptionA potent antagonist of GABA receptors (IC50 = 240 nM) at synapses in the central nervous system. Inhibits 35S-TBPS binding to the Cl- channel (IC50 = 1.7 µM). Picrotoxin is a mixture of one mole of picrotoxinin and one mole of picrotin.
      FormWhite to light yellow powder or crystals
      CAS number124-87-8
      RTECSTJ9100000
      Chemical formulaC₁₅H₁₈O₇ . C₁₅H₁₆O₆
      Structure formulaStructure formula
      Purity≥98% (mixture of Picrotoxin and picrotin) by HPLC
      SolubilityEthanol (50 mg/ml) or basic aqueous solutions (3 mg/ml)
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Toxicity Highly Toxic
      Merck USA index14, 7415
      ReferencesQian, H., and Dowling, J.E. 1994. J. Neurosci. 14, 4299.
      Yoon, K.W., et al. 1993. J. Physiol. 464, 423.
      Akaike, N., et al. 1985. Experientia 41, 70.