Millipore Sigma Vibrant Logo

524751 Phosphodiesterase 7A1, Human, Recombinant, S. frugiperda

MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: hPDE7A1

View Products on Sigmaaldrich.com
524751
Visualizza prezzi e disponibilità

Panoramica

Replacement Information

Prezzi e disponibilità

Numero di catalogo DisponibilitàConfezionamento Qtà/conf Prezzo Quantità
524751-10U
Verifica della disponibilità in corso...
—
Disponibilità limitata Disponibilità limitata
A magazzino 
Fuori produzione
Disponibili quantità limitate
La disponibilità deve essere confermata
    Prodotti rimanenti: riceverà un nostro avviso
      Prodotti rimanenti: riceverà un nostro avviso
      Will advise
      Contatti il Servizio Clienti
      Contact Customer Service

      		 Fiala di plastica 10 u
      Ricerca del prezzo in corso...
      Non è stato possibile trovare il prezzo
      La quantità minima deve essere un multiplo di
      Maximum Quantity is
      Al termine dell'ordine Maggiori informazioni
      Lei ha salvato ()
       
      —
      Richiedi il prezzo
      		 —
      Description
      OverviewFull-length, recombinant, human phosphodiesterdase 7A1 (PDE7A1) expressed in S. frugiperda insect cells using a baculovirus expression system. PDE7A1 is required for T-cell activation induced by the costimulation of CD3 and CD28 receptors. Increased PDE7A1 correlates with a decrease in cAMP, increased IL-2, and increased cell proliferation. Supplied as a partially purified preparation of catalytically active enzyme useful for inhibitor and activator assays.
      Catalogue Number524751
      Brand Family Calbiochem®
      SynonymshPDE7A1
      Application Data
      Increasing concentrations of SB36207, a PDE7A1 inhibitor, were mixed with the enzyme and the activity was measured.
      References
      ReferencesHan, P., et al. 2006. J. Biol. Chem. 281, 15050.
      Lugnier, C. 2006. Pharmacol Ther. 109, 366.
      Bloom, T.J., and Beavo, J.A. 1996. Proc. Natl. Acad. Sci. U S A 93, 14188.
      Product Information
      Activity≥ 0.5 U/µl
      Unit of DefinitionOne unit is defined as the amount of enzyme that is required to convert 1 pmol cAMP to AMP per min at 30°C, pH 7.5.
      FormLiquid
      FormulationIn 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3.
      Quality LevelMQ100
      Applications
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      524751-10U 04055977197099

      Documentation

      Phosphodiesterase 7A1, Human, Recombinant, S. frugiperda MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      Phosphodiesterase 7A1, Human, Recombinant, S. frugiperda Certificati d'Analisi

      TitoloNumero di lotto
      524751

      Riferimenti bibliografici

      Panoramica delle referenze
      Han, P., et al. 2006. J. Biol. Chem. 281, 15050.
      Lugnier, C. 2006. Pharmacol Ther. 109, 366.
      Bloom, T.J., and Beavo, J.A. 1996. Proc. Natl. Acad. Sci. U S A 93, 14188.
      Scheda tecnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision17-December-2008 JSW
      SynonymshPDE7A1
      Application Data
      Increasing concentrations of SB36207, a PDE7A1 inhibitor, were mixed with the enzyme and the activity was measured.
      DescriptionFull-length, recombinant, human phosphodiesterdase 7A1 (PDE7A1) expressed in S. frugiperda insect cells using a baculovirus expression system. PDE7A1 is required for T-cell activation induced by the costimulation of CD3 and CD28 receptors. Increased PDE7A1 correlates with a decrease in cAMP, increased IL-2, and increased cell proliferation. Supplied as a partially purified preparation of catalytically active enzyme useful for inhibitor and activator assays.
      FormLiquid
      FormulationIn 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3.
      Activity≥ 0.5 U/µl
      Unit definitionOne unit is defined as the amount of enzyme that is required to convert 1 pmol cAMP to AMP per min at 30°C, pH 7.5.
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesHan, P., et al. 2006. J. Biol. Chem. 281, 15050.
      Lugnier, C. 2006. Pharmacol Ther. 109, 366.
      Bloom, T.J., and Beavo, J.A. 1996. Proc. Natl. Acad. Sci. U S A 93, 14188.