516481 Sigma-AldrichPepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem
Pepstatin A, Synthetic, CAS 26305-03-3, is a reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin.
More>> Pepstatin A, Synthetic, CAS 26305-03-3, is a reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Less<<Sinonimi: Iva-Val-Val-Sta-Ala-Sta, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid
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Panoramica
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Tabella delle specifiche principali
CAS # | Empirical Formula |
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26305-03-3 | C₃₄H₆₃N₅O₉ |
Prezzi e disponibilità
Numero di catalogo | Disponibilità | Confezionamento | Qtà/conf | Prezzo | Quantità | |
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516481-100MG |
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Fiala di plastica | 100 mg |
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516481-25MG |
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Fiala di plastica | 25 mg |
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516481-5MG |
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Fiala di plastica | 5 mg |
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Description | |
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Overview | A reversible inhibitor of aspartic proteases. Inhibits cathepsin D, pepsin, and renin. Reported to block apoptosis induced by CA-074 (Cat. No. 205530) in PC12 cell lines. Also available as a 25 mM solution in DMSO (Cat. No. 508437). |
Effective concentration: 1.0 µM. | |
Catalogue Number | 516481 |
Brand Family | Calbiochem® |
Synonyms | Iva-Val-Val-Sta-Ala-Sta, Isovaleryl-Val-Val-4-amino-3-hydroxy-6-methylheptanoyl-Ala-4-amino-3-hydroxy-6-methylheptanoic Acid |
Product Information | |
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CAS number | 26305-03-3 |
ATP Competitive | N |
Form | White solid |
Hill Formula | C₃₄H₆₃N₅O₉ |
Chemical formula | C₃₄H₆₃N₅O₉ |
Optical rotation | Optical rotation: -90.0 ± 5° (c = 0.5, MeOH, 20°C). |
Reversible | Y |
Quality Level | MQ100 |
Applications |
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Biological Information | |
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Primary Target | cathepsin D |
Primary Target IC<sub>50</sub> | EC50 = 1.0 µM in blocking apoptosis induced by CA-074 in PC12 cell lines |
Purity | ≥98% by HPLC |
Physicochemical Information | |
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Cell permeable | N |
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Materials Information |
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Toxicological Information |
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Safety Information according to GHS | |
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RTECS | SC6155000 |
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Packaging Information |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Numero di catalogo | GTIN |
516481-100MG | 04055977198812 |
516481-25MG | 07790788055837 |
516481-5MG | 04055977198836 |
Documentation
Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem MSDS
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Pepstatin A, Synthetic - CAS 26305-03-3 - Calbiochem Certificati d'Analisi
Titolo | Numero di lotto |
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516481 |
Riferimenti bibliografici
Panoramica delle referenze |
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Isahara, K., et al. 1999. Neuroscience 91, 233. Kanamori, S., et al. 1998. Biochem. Biophys. Res. Commun. 251, 204. Szewczuk, Z., et al. 1992. Int. J. Pept. Prot. Res. 40, 233. Carraway, R.E., et al. 1991. Peptides 12, 107. Eid, M., et al. 1981. Biochem. J. 197, 465. Umezawa, H., et al. 1970. J. Antibiot. 23, 259. |
Brochure
Titolo |
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Western Blotting Tools |
Informazioni tecniche
Titolo |
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Protein Blotting Handbook: 6th Edition |