Millipore Sigma Vibrant Logo

580556 Paclitaxel, Semi-Synthetic - CAS 33069-62-4 - Calbiochem

A semi-synthetic form of Paclitaxel having no contamination by natural taxanes. Also has reduced levels of epimerization products as contaminants.

MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
Primary Target: Promotes assembly of microtubules and inhibits tubulin disassembly.
View Products on Sigmaaldrich.com
580556
Visualizza prezzi e disponibilità

Panoramica

Replacement Information

Tabella delle specifiche principali

CAS #Empirical Formula
33069-62-4C₄₇H₅₁NO₁₄

Prezzi e disponibilità

Numero di catalogo DisponibilitàConfezionamento Qtà/conf Prezzo Quantità
580556-5MG
Verifica della disponibilità in corso...
—
Disponibilità limitata Disponibilità limitata
A magazzino 
Fuori produzione
Disponibili quantità limitate
La disponibilità deve essere confermata
    Prodotti rimanenti: riceverà un nostro avviso
      Prodotti rimanenti: riceverà un nostro avviso
      Will advise
      Contatti il Servizio Clienti
      Contact Customer Service

      		 Fiala di plastica 5 mg
      Ricerca del prezzo in corso...
      Non è stato possibile trovare il prezzo
      La quantità minima deve essere un multiplo di
      Maximum Quantity is
      Al termine dell'ordine Maggiori informazioni
      Lei ha salvato ()
       
      —
      Richiedi il prezzo
      		 —
      Description
      OverviewA semi-synthetic form of Paclitaxel (Cat. No. 580555) having no contamination by natural taxanes. Also has reduced levels of epimerization products as contaminants.
      Catalogue Number580556
      Brand Family Calbiochem®
      References
      ReferencesDerry, W.B., et al. 1995. Biochemistry 34, 2203.
      Milas, L., et al. 1995. Cancer Chemother. Pharmacol. 35, 297.
      Donaldson, K.L., et al. 1994. Int. J. Cancer 57, 847.
      Hornback, N.B., et al. 1994. In Vivo 8, 819.
      Manthey, C.L., et al. 1992. J. Immunol. 149, 2459.
      Rowinsky, E.K., et al. 1992. Semin. Oncol.19, 646.
      Ding, A.H., et al. 1990. Science 248, 370.
      Mogensen, M.M. and Tucker, J.B. 1990. J. Cell Sci. 97, 101.
      Slichenmeyer, W.J. and Von Hoff, D.D. 1990. J. Clin. Pharmacol. 30, 770.
      Product Information
      CAS number33069-62-4
      ATP CompetitiveN
      FormCrystalline solid
      Hill FormulaC₄₇H₅₁NO₁₄
      Chemical formulaC₄₇H₅₁NO₁₄
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPromotes assembly of microtubules and inhibits tubulin disassembly.
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSDA8340700
      Safety Information
      R PhraseR: 37/38-41-46-60

      Irritating to respiratory system and skin.
      Risk of serious damage to eyes.
      May cause heritable genetic damage.
      May impair fertility.
      S PhraseS: 22-26-36/37/39-45

      Do not breathe dust.
      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Carcinogenic / Teratogenic
      Storage -20°C
      Protect from Light Protect from light
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      580556-5MG 04055977265538

      Documentation

      Paclitaxel, Semi-Synthetic - CAS 33069-62-4 - Calbiochem MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      Paclitaxel, Semi-Synthetic - CAS 33069-62-4 - Calbiochem Certificati d'Analisi

      TitoloNumero di lotto
      580556

      Riferimenti bibliografici

      Panoramica delle referenze
      Derry, W.B., et al. 1995. Biochemistry 34, 2203.
      Milas, L., et al. 1995. Cancer Chemother. Pharmacol. 35, 297.
      Donaldson, K.L., et al. 1994. Int. J. Cancer 57, 847.
      Hornback, N.B., et al. 1994. In Vivo 8, 819.
      Manthey, C.L., et al. 1992. J. Immunol. 149, 2459.
      Rowinsky, E.K., et al. 1992. Semin. Oncol.19, 646.
      Ding, A.H., et al. 1990. Science 248, 370.
      Mogensen, M.M. and Tucker, J.B. 1990. J. Cell Sci. 97, 101.
      Slichenmeyer, W.J. and Von Hoff, D.D. 1990. J. Clin. Pharmacol. 30, 770.
      Scheda tecnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-May-2011 JSW
      DescriptionA semi-synthetically derived form of Paclitaxel (TAXOL®, Cat. No. 580555) having no contamination of natural taxanes. Also has less epimerization products as contaminants. Promotes assembly of microtubules and inhibits tubulin disassembly. An effective agent in blocking HeLa and B16 cells at the G2/M stage. Inhibits DNA synthesis and stimulates the release of tumor necrosis factor-α. Induces apoptosis in murine mammary carcinoma MCA-4 and ovarian carcinoma OCA-1 tumors.
      FormCrystalline solid
      CAS number33069-62-4
      RTECSDA8340700
      Chemical formulaC₄₇H₅₁NO₁₄
      Purity≥97% by HPLC
      SolubilityDMSO or methanol
      Storage Protect from moisture
      Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Carcinogenic / Teratogenic
      Merck USA index14, 6982
      ReferencesDerry, W.B., et al. 1995. Biochemistry 34, 2203.
      Milas, L., et al. 1995. Cancer Chemother. Pharmacol. 35, 297.
      Donaldson, K.L., et al. 1994. Int. J. Cancer 57, 847.
      Hornback, N.B., et al. 1994. In Vivo 8, 819.
      Manthey, C.L., et al. 1992. J. Immunol. 149, 2459.
      Rowinsky, E.K., et al. 1992. Semin. Oncol.19, 646.
      Ding, A.H., et al. 1990. Science 248, 370.
      Mogensen, M.M. and Tucker, J.B. 1990. J. Cell Sci. 97, 101.
      Slichenmeyer, W.J. and Von Hoff, D.D. 1990. J. Clin. Pharmacol. 30, 770.

      Prodotti e applicazioni correlate

      Alternative Products

      Numero di catalogo Descrizione  
      580555 Paclitaxel, Taxus sp. - CAS 33069-62-4 - Calbiochem Prezzi e disponibilità

      Categorie

      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Extracellular Matrix, Adhesion and Cytoskeletal Research Tools