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539522 PKCε Translocation Inhibitor Peptide - Calbiochem

The PKCε Translocation Inhibitor Peptide, Negative Control controls the biological activity of PKCε. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: Protein Kinase Cε Translocation Inhibitor I, EAVSLKPT, PKCε Translocation Inhibitor I, PKCε-RACK2 Interaction Inhibitor I

Primary Target: PKCε Translocation
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539522
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Panoramica

Replacement Information

Tabella delle specifiche principali

Empirical Formula
C₃₇H₆₅N₉O₁₃

Prezzi e disponibilità

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539522-5MG
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      Description
      OverviewAn octapeptide that selectively inhibits the translocation of protein kinase Cε to subcellular sites in a reversible manner. Inhibition of PKCε translocation is known to specifically block phorbol ester- or norepinephrine-mediated regulation of contraction in cardiomyocytes.
      Catalogue Number539522
      Brand Family Calbiochem®
      SynonymsProtein Kinase Cε Translocation Inhibitor I, EAVSLKPT, PKCε Translocation Inhibitor I, PKCε-RACK2 Interaction Inhibitor I
      References
      ReferencesYedovitzky, M., et al. 1997. J. Biol. Chem. 272, 1417.
      Johnson, J.A., et al. 1996. J. Biol. Chem. 271, 24962.
      Product Information
      ATP CompetitiveN
      DeclarationSold under license of U.S. Patent 5,783,405.
      FormWhite lyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₃₇H₆₅N₉O₁₃
      Chemical formulaC₃₇H₆₅N₉O₁₃
      Hygroscopic Hygroscopic
      ReversibleY
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPKCε Translocation
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceH-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      539522-5MG 04055977194630

      Documentation

      PKCε Translocation Inhibitor Peptide - Calbiochem MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      PKCε Translocation Inhibitor Peptide - Calbiochem Certificati d'Analisi

      TitoloNumero di lotto
      539522

      Riferimenti bibliografici

      Panoramica delle referenze
      Yedovitzky, M., et al. 1997. J. Biol. Chem. 272, 1417.
      Johnson, J.A., et al. 1996. J. Biol. Chem. 271, 24962.

      Citazioni

      Titolo
    • Lawrence, K.M., et al. 2005. FASEB Journal 19, 831-833.
    • Dai, Y., et al. 2004. Journal of Neuroscience 24, 4293.
      		•
      Scheda tecnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-September-2008 RFH
      SynonymsProtein Kinase Cε Translocation Inhibitor I, EAVSLKPT, PKCε Translocation Inhibitor I, PKCε-RACK2 Interaction Inhibitor I
      DescriptionAn octapeptide that selectively inhibits the translocation of PKCε to subcellular sites. Inhibition of PKCε translocation is known to specifically block phorbol ester or norepinephrine-mediated regulation of contraction in cardiomyocytes.
      FormWhite lyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₃₇H₆₅N₉O₁₃
      Peptide SequenceH-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH
      Purity≥97% by HPLC
      SolubilityH₂O (3 mg/ml)
      Storage +2°C to +8°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesYedovitzky, M., et al. 1997. J. Biol. Chem. 272, 1417.
      Johnson, J.A., et al. 1996. J. Biol. Chem. 271, 24962.
      Citation
    • Lawrence, K.M., et al. 2005. FASEB Journal 19, 831-833.
    • Dai, Y., et al. 2004. Journal of Neuroscience 24, 4293.
      		•