Millipore Sigma Vibrant Logo

20-133A PKC Lipid Activator

PKC Lipid Activator: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
View Products on Sigmaaldrich.com
20-133A
5 mL  
Ricerca del prezzo in corso...
Non è stato possibile trovare il prezzo
La quantità minima deve essere un multiplo di
Maximum Quantity is
Al termine dell'ordine Maggiori informazioni
Lei ha salvato ()
 
—
Richiedi il prezzo
—
Disponibilità limitata Disponibilità limitata
A magazzino 
Fuori produzione
Disponibili quantità limitate
La disponibilità deve essere confermata
    Prodotti rimanenti: riceverà un nostro avviso
      Prodotti rimanenti: riceverà un nostro avviso
      Will advise
      Contatti il Servizio Clienti
      Contact Customer Service

       

      Contatti il Servizio Clienti

      Panoramica

      Replacement Information
      Description
      Catalogue Number20-133A
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionPKC Lipid Activator
      References
      Product Information
      Quality LevelMQ100
      Applications
      Biological Information
      Entrez Gene Number
      Entrez Gene SummaryProtein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
      Gene Symbol
      • PRKCA
      • PKC-A
      • PKCA
      • PRKACA
      • PKC-alpha
      • MGC129901
      • AAG6
      • MGC129900
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P17252 # PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
      COFACTOR: Binds 3 calcium ions per subunit. The ions are bound to the C2 domain (By similarity).
      SIZE: 672 amino acids; 76764 Da
      SUBUNIT: Interacts with CENTA1, CSPG4 and PRKCABP. Binds to SDPR in the presence of phosphatidylserine.
      SIMILARITY: SwissProt: P17252 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 C2 domain. & Contains 2 phorbol-ester/DAG-type zinc fingers. & Contains 1 protein kinase domain.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditionsstable 1 year at -20°C from date of shipment
      Packaging Information
      Material Size5 mL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      20-133A 04053252362835

      Documentation

      PKC Lipid Activator MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      PKC Lipid Activator Certificati d'Analisi

      TitoloNumero di lotto
      PKC Lipid Activator 3002727
      PKC Lipid Activator 2859881
      PKC Lipid Activator 3025999
      PKC Lipid Activator - 2115690 2115690
      PKC Lipid Activator - 2394242 2394242
      PKC Lipid Activator - 0610042807 0610042807
      PKC Lipid Activator - 0703054493 0703054493
      PKC Lipid Activator - 2148518 2148518
      PKC Lipid Activator - 2206393 2206393
      PKC Lipid Activator - 2297437 2297437
      Show more