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528822 PARP Inhibitor XII - CAS 489457-67-2 - Calbiochem

The PARP Inhibitor XII, also referenced under CAS 489457-67-2, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.

MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: 3-(4-Chlorophenyl)quinoxaline-5-carboxamide

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528822
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Tabella delle specifiche principali

CAS #Empirical Formula
489457-67-2C₁₅H₁₀ClN₃O

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528822-5MG
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      Description
      OverviewA potent quinoxaline-based PARP inhibitor with a ~5-fold selectivity towards PARP-2 over PARP-1 (IC50 = 7 and 33 nM, respectively). Reported to be brain-permeant and exhibit good pharmacokinetics.
      Catalogue Number528822
      Brand Family Calbiochem®
      Synonyms3-(4-Chlorophenyl)quinoxaline-5-carboxamide
      References
      ReferencesIshida, J., et al. 2006. Bioorg. Med. Chem. 14, 1378.
      Iwashita, A., et al. 2005. FEBS Lett. 579, 1389.
      Product Information
      CAS number489457-67-2
      FormLight brown solid
      Hill FormulaC₁₅H₁₀ClN₃O
      Chemical formulaC₁₅H₁₀ClN₃O
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      528822-5MG 04055977196634

      Documentation

      PARP Inhibitor XII - CAS 489457-67-2 - Calbiochem MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      PARP Inhibitor XII - CAS 489457-67-2 - Calbiochem Certificati d'Analisi

      TitoloNumero di lotto
      528822

      Riferimenti bibliografici

      Panoramica delle referenze
      Ishida, J., et al. 2006. Bioorg. Med. Chem. 14, 1378.
      Iwashita, A., et al. 2005. FEBS Lett. 579, 1389.
      Scheda tecnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-April-2011 RFH
      Synonyms3-(4-Chlorophenyl)quinoxaline-5-carboxamide
      DescriptionA potent quinoxaline-based PARP inhibitor with a ~5-fold selectivity towards PARP-2 over PARP-1 (IC50 = 7 and 33 nM, respectively). Reported to be brain-permeant and exhibit good pharmacokinetics.
      FormLight brown solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number489457-67-2
      Chemical formulaC₁₅H₁₀ClN₃O
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (10 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Irritant
      ReferencesIshida, J., et al. 2006. Bioorg. Med. Chem. 14, 1378.
      Iwashita, A., et al. 2005. FEBS Lett. 579, 1389.