Millipore Sigma Vibrant Logo

480402 NFAT Inhibitor - CAS 249537-73-3 - Calbiochem

View Products on Sigmaaldrich.com
480402
Visualizza prezzi e disponibilità

Panoramica

Replacement Information

Tabella delle specifiche principali

CAS #Empirical Formula
249537-73-3C₇₅H₁₁₈N₂₀O₂₂S

Prezzi e disponibilità

Numero di catalogo DisponibilitàConfezionamento Qtà/conf Prezzo Quantità
480402-500UG
Verifica della disponibilità in corso...
Disponibilità limitata
Disponibilità limitata
A magazzino 
Fuori produzione
Disponibili quantità limitate
La disponibilità deve essere confermata
    Prodotti rimanenti: riceverà un nostro avviso
      Prodotti rimanenti: riceverà un nostro avviso
      Will advise
      Contatti il Servizio Clienti
      Contact Customer Service

      Fiala di plastica 500 μg
      Ricerca del prezzo in corso...
      Non è stato possibile trovare il prezzo
      La quantità minima deve essere un multiplo di
      Maximum Quantity is
      Al termine dell'ordine Maggiori informazioni
      Lei ha salvato ()
       
      Richiedi il prezzo
      Description
      OverviewA highly selective NFAT (Nuclear Factor of Activated T-cells) inhibitor that interferes with calcineurin-NFAT interaction without affecting calcineurin (Cat. No. 539568) phosphatase activity. Inhibits NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells, without affecting the expression of other cytokines that require calcineurin but not NFAT.
      Catalogue Number480402
      Brand Family Calbiochem®
      SynonymsMAGPHPVIVITGPHEE
      References
      ReferencesNoguchi, H., et al. 2004. Nat. Med. 10, 305.
      Kiani, A., et al. 2001. Blood 98, 1480.
      Aramburu, J., et al. 1999. Science 285, 2129.
      Product Information
      CAS number249537-73-3
      ATP CompetitiveN
      FormLyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₇₅H₁₁₈N₂₀O₂₂S
      Chemical formulaC₇₅H₁₁₈N₂₀O₂₂S
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetNFAT (Nuclear Factor of Activated T-cells)
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceH-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Avoid freeze/thaw cycles of solutions.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      480402-500UG 07790788050658

      Documentation

      NFAT Inhibitor - CAS 249537-73-3 - Calbiochem MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      NFAT Inhibitor - CAS 249537-73-3 - Calbiochem Certificati d'Analisi

      TitoloNumero di lotto
      480402

      Riferimenti bibliografici

      Panoramica delle referenze
      Noguchi, H., et al. 2004. Nat. Med. 10, 305.
      Kiani, A., et al. 2001. Blood 98, 1480.
      Aramburu, J., et al. 1999. Science 285, 2129.
      Scheda tecnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-August-2008 RFH
      SynonymsMAGPHPVIVITGPHEE
      DescriptionA highly selective NFAT inhibitor that prevents NFAT activation and NFAT-dependent expression of endogenous cytokine genes in T cells. Does not affect the expression of other cytokines requiring calcineurin, but not NFAT. Inhibits calcineurin-mediated dephosphorylation of NFAT1, NFAT2, and NFAT4 in cell extracts.
      FormLyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Intert gas (Yes/No) Packaged under inert gas
      CAS number249537-73-3
      Chemical formulaC₇₅H₁₁₈N₂₀O₂₂S
      Peptide SequenceH-Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu-OH
      Purity≥95% by HPLC
      SolubilityH₂O
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Avoid freeze/thaw cycles of solutions.
      Toxicity Standard Handling
      ReferencesNoguchi, H., et al. 2004. Nat. Med. 10, 305.
      Kiani, A., et al. 2001. Blood 98, 1480.
      Aramburu, J., et al. 1999. Science 285, 2129.