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444286 MMP-2 Inhibitor II - CAS 869577-51-5 - Calbiochem

The MMP-2 Inhibitor II, also referenced under CAS 869577-51-5, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: (4-(4-(Methanesulfonamido)phenoxy)phenylsulfonyl)methyloxirane

Primary Target: MMP-2
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444286
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Tabella delle specifiche principali

CAS #Empirical Formula
869577-51-5C₁₆H₁₇NO₆S₂

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444286-5MG
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      Description
      OverviewAn oxirane analog of SB-3CT, pMS (Cat. No. 444285) that acts as a selective, active site-binding, irreversible inhibitor of MMP-2 (Ki = 2.4 µM). Although less potent, it exhibits enhanced selectivity towards MMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively) than SB-3CT, pMS.
      Catalogue Number444286
      Brand Family Calbiochem®
      Synonyms(4-(4-(Methanesulfonamido)phenoxy)phenylsulfonyl)methyloxirane
      References
      ReferencesIkejiri, M., et al. 2005. J. Biol. Chem. 280, 33992.
      Product Information
      CAS number869577-51-5
      FormWhite solid
      Hill FormulaC₁₆H₁₇NO₆S₂
      Chemical formulaC₁₆H₁₇NO₆S₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetMMP-2
      Primary Target K<sub>i</sub>2.4 µM
      Secondary targetMMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively)
      Purity≥97% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      444286-5MG 04055977186031

      Documentation

      MMP-2 Inhibitor II - CAS 869577-51-5 - Calbiochem MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      MMP-2 Inhibitor II - CAS 869577-51-5 - Calbiochem Certificati d'Analisi

      TitoloNumero di lotto
      444286

      Riferimenti bibliografici

      Panoramica delle referenze
      Ikejiri, M., et al. 2005. J. Biol. Chem. 280, 33992.
      Scheda tecnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-April-2011 RFH
      Synonyms(4-(4-(Methanesulfonamido)phenoxy)phenylsulfonyl)methyloxirane
      DescriptionAn oxirane analog of SB-3CT, pMS (Cat. No. 444285) that acts as a selective, active site-binding, irreversible inhibitor of MMP-2 (Ki = 2.4 µM). Although less potent, it exhibits enhanced selectivity towards MMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively) than SB-3CT, pMS.
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number869577-51-5
      Chemical formulaC₁₆H₁₇NO₆S₂
      Structure formulaStructure formula
      Purity≥97% by HPLC
      SolubilityDMSO (200 mg/ml)
      Storage Protect from moisture
      Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Standard Handling
      ReferencesIkejiri, M., et al. 2005. J. Biol. Chem. 280, 33992.