Millipore Sigma Vibrant Logo

524644 L-α-Phosphatidyl-D-myo-inositol-4,5-bisphosphate, Triammonium Salt, Porcine Brain - CAS 383907-42-4 - Calbiochem

A component of membrane-bound receptors in association with phospholipase C (PLC).

MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: PIP₂

View Products on Sigmaaldrich.com
524644
Visualizza prezzi e disponibilità

Panoramica

Replacement Information

Tabella delle specifiche principali

CAS #Empirical Formula
383907-42-4C₄₇H₈₂O₁₉P₃ · 3NH₄

Prezzi e disponibilità

Numero di catalogo DisponibilitàConfezionamento Qtà/conf Prezzo Quantità
524644-100UG
Verifica della disponibilità in corso...
—
Disponibilità limitata Disponibilità limitata
A magazzino 
Fuori produzione
Disponibili quantità limitate
La disponibilità deve essere confermata
    Prodotti rimanenti: riceverà un nostro avviso
      Prodotti rimanenti: riceverà un nostro avviso
      Will advise
      Contatti il Servizio Clienti
      Contact Customer Service

      		 Fiala di plastica 100 μg
      Ricerca del prezzo in corso...
      Non è stato possibile trovare il prezzo
      La quantità minima deve essere un multiplo di
      Maximum Quantity is
      Al termine dell'ordine Maggiori informazioni
      Lei ha salvato ()
       
      —
      Richiedi il prezzo
      		 —
      524644-1MG
      Verifica della disponibilità in corso...
      —
      Disponibilità limitata Disponibilità limitata
      A magazzino 
      Fuori produzione
      Disponibili quantità limitate
      La disponibilità deve essere confermata
        Prodotti rimanenti: riceverà un nostro avviso
          Prodotti rimanenti: riceverà un nostro avviso
          Will advise
          Contatti il Servizio Clienti
          Contact Customer Service

          		 Fiala di plastica 1 mg
          Ricerca del prezzo in corso...
          Non è stato possibile trovare il prezzo
          La quantità minima deve essere un multiplo di
          Maximum Quantity is
          Al termine dell'ordine Maggiori informazioni
          Lei ha salvato ()
           
          —
          Richiedi il prezzo
          		 —
          Description
          OverviewA component of membrane-bound receptors in association with phospholipase C (PLC). Potently stimulates brain phospholipase D (PLD) activity in vitro. Has been shown to activate protein kinase C (PKC) in the presence of phosphatidylserine and Ca2+. Antagonist of ATP-sensitive potassium (KATP) channels when applied to inside-out membrane patches.
          Catalogue Number524644
          Brand Family Calbiochem®
          SynonymsPIP₂
          References
          ReferencesBaukrowitz, T., et al. 1998. Science 282, 1141.
          Shyng, S.-L., and Nichols, C.G. 1998. Science 282, 1138.
          Mazzotti, G., et al. 1995. J. Histochem. Cytochem. 43, 181.
          Liscovitch, M., et al. 1994. J. Biol. Chem. 269, 21403.
          Chauhan, A., et al. 1991. Biochem. Biophys. Res. Commun. 175, 852.
          Williamson, J.R. 1986. Hypertension 8, 140.
          Berridge, M.J., and Irvine, R.F. 1984. Nature 312, 315.
          Product Information
          CAS number383907-42-4
          ATP CompetitiveN
          FormWhite to off-white solid
          Hill FormulaC₄₇H₈₂O₁₉P₃ · 3NH₄
          Chemical formulaC₄₇H₈₂O₁₉P₃ · 3NH₄
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetBrain phospholipase D (PLD)
          Purity≥98% by TLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 36/37/38

          Irritating to eyes, respiratory system and skin.
          S PhraseS: 26-36

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Dry Ice Only
          Toxicity Irritant
          Storage ≤ -70°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution in H₂O, store in the refrigerator (4°C). Do not freeze aqueous solutions. Following reconstitution in chloroform, aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 2 days at 4°C. Chloroform stock solutions are stable for up to 1 month at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Numero di catalogo GTIN
          524644-100UG 04055977197624
          524644-1MG 04055977197617

          Documentation

          L-α-Phosphatidyl-D-myo-inositol-4,5-bisphosphate, Triammonium Salt, Porcine Brain - CAS 383907-42-4 - Calbiochem MSDS

          Titolo

          Scheda di sicurezza (MSDS) 

          L-α-Phosphatidyl-D-myo-inositol-4,5-bisphosphate, Triammonium Salt, Porcine Brain - CAS 383907-42-4 - Calbiochem Certificati d'Analisi

          TitoloNumero di lotto
          524644

          Riferimenti bibliografici

          Panoramica delle referenze
          Baukrowitz, T., et al. 1998. Science 282, 1141.
          Shyng, S.-L., and Nichols, C.G. 1998. Science 282, 1138.
          Mazzotti, G., et al. 1995. J. Histochem. Cytochem. 43, 181.
          Liscovitch, M., et al. 1994. J. Biol. Chem. 269, 21403.
          Chauhan, A., et al. 1991. Biochem. Biophys. Res. Commun. 175, 852.
          Williamson, J.R. 1986. Hypertension 8, 140.
          Berridge, M.J., and Irvine, R.F. 1984. Nature 312, 315.
          Scheda tecnica

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision03-August-2015 JSW
          SynonymsPIP₂
          DescriptionA component of membrane-bound receptors in association with phospholipase C. Hydrolysis of PIP2 yields IP3 and diacylglycerol, causing the release of intracellular Ca2+ and activation of protein kinase C. Potently stimulates phospholipase D activity in vitro in brain tissue. A substrate for PI 3-kinase. Antagonist of ATP inhibtion of ATP-sensitive potassium (KATP) channels when applied to inside-out membrane patches.

          Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.
          FormWhite to off-white solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number383907-42-4
          Chemical formulaC₄₇H₈₂O₁₉P₃ · 3NH₄
          Structure formulaStructure formula
          Purity≥98% by TLC
          SolubilityCHCl₃ (50 mg/ml) or H₂O (10 mg/ml)
          Storage Protect from light
          ≤ -70°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution in H₂O, store in the refrigerator (4°C). Do not freeze aqueous solutions. Following reconstitution in chloroform, aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 2 days at 4°C. Chloroform stock solutions are stable for up to 1 month at -20°C.
          Toxicity Irritant
          ReferencesBaukrowitz, T., et al. 1998. Science 282, 1141.
          Shyng, S.-L., and Nichols, C.G. 1998. Science 282, 1138.
          Mazzotti, G., et al. 1995. J. Histochem. Cytochem. 43, 181.
          Liscovitch, M., et al. 1994. J. Biol. Chem. 269, 21403.
          Chauhan, A., et al. 1991. Biochem. Biophys. Res. Commun. 175, 852.
          Williamson, J.R. 1986. Hypertension 8, 140.
          Berridge, M.J., and Irvine, R.F. 1984. Nature 312, 315.