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539749 InSolution™ PTP1B Inhibitor - Calbiochem

The InSolution™ PTP1B Inhibitor controls the biological activity of PTP1B. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

InSolution™ PTP1B Inhibitor - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: PTP Inhibitor XXII

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539749
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Panoramica

Replacement Information

Tabella delle specifiche principali

Empirical Formula
C₂₆H₁₉Br₂N₃O₇S₃

Prezzi e disponibilità

Numero di catalogo DisponibilitàConfezionamento Qtà/conf Prezzo Quantità
539749-2MG
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      Description
      OverviewA cell-permeable, selective, reversible, and non-competitive allosteric inhibitor of PTP1B (IC50 = 4 µM and 8 µM for PTP1B403 and PTP1B298, respectively). Binds to a novel site away from the catalytic pocket and inhibits PTP1B activity by preventing closure of the WPD loop.
      Catalogue Number539749
      Brand Family Calbiochem®
      SynonymsPTP Inhibitor XXII
      References
      ReferencesWiesmann, C., et al. 2004. Nat. Struct. Mol. Biol. 11, 730.
      Product Information
      FormLiquid
      FormulationA 10 mM (2 mg/270 µl) solution of PTP1B Inhibitor (Cat. No. 539741) in DMSO.
      Hill FormulaC₂₆H₁₉Br₂N₃O₇S₃
      Chemical formulaC₂₆H₁₉Br₂N₃O₇S₃
      Hygroscopic Hygroscopic
      ReversibleY
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Target IC<sub>50</sub>IC50 = 4 and 8 µM for PTP1B403 and PTP1B298, respectively
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/38

      Irritating to eyes and skin.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Irritant
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      539749-2MG 04055977194364

      Documentation

      InSolution™ PTP1B Inhibitor - Calbiochem MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      InSolution™ PTP1B Inhibitor - Calbiochem Certificati d'Analisi

      TitoloNumero di lotto
      539749

      Riferimenti bibliografici

      Panoramica delle referenze
      Wiesmann, C., et al. 2004. Nat. Struct. Mol. Biol. 11, 730.
      Scheda tecnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision22-November-2011 RFH
      SynonymsPTP Inhibitor XXII
      DescriptionA cell-permeable, selective, reversible, and non-competitive allosteric inhibitor of PTP1B (IC50 = 4 µM and 8 µM for PTP1B403 and PTP1B298, respectively). Binds to a novel site away from the catalytic pocket and inhibits PTP1B activity by preventing closure of the WPD loop.
      FormLiquid
      FormulationA 10 mM (2 mg/270 µl) solution of PTP1B Inhibitor (Cat. No. 539741) in DMSO.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₂₆H₁₉Br₂N₃O₇S₃
      Structure formulaStructure formula
      Purity≥97% by HPLC
      Storage Protect from light
      Avoid freeze/thaw
      -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Irritant
      ReferencesWiesmann, C., et al. 2004. Nat. Struct. Mol. Biol. 11, 730.