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385880 Hsp25 Kinase Inhibitor - Calbiochem

The Hsp25 Kinase Inhibitor controls the biological activity of Hsp25 KInase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Hsp25 Kinase Inhibitor - Calbiochem: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: MK2 Inhibitor, KKKALNRQLGVAA, MAPKAP Kinase-2 Inhibitor

Primary Target: (Hsp25) kinase
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385880
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Panoramica

Replacement Information

Tabella delle specifiche principali

Empirical Formula
C₆₁H₁₁₃N₂₁O₁₆

Prezzi e disponibilità

Numero di catalogo DisponibilitàConfezionamento Qtà/conf Prezzo Quantità
385880-1MG
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      Description
      OverviewA 13-residue, cell-permeable peptide that acts as a potent and selective inhibitor of mammalian heat-shock protein (Hsp25) kinase [also called mitogen-activated protein kinase-activated protein kinase-2 (MAPKAP kinase-2)]. Inhibition is competitive with respect to the substrate peptide (Ki = 8.1 µM) and non-competitive with respect to ATP (Ki = 134 µM).
      Catalogue Number385880
      Brand Family Calbiochem®
      SynonymsMK2 Inhibitor, KKKALNRQLGVAA, MAPKAP Kinase-2 Inhibitor
      References
      ReferencesKatsoulidis, E., et al. 2005. Cancer Res. 65, 9029.
      Hayess, K., and Benndorf, R. 1997. Biochem. Pharmacol. 53, 1239.
      Product Information
      ATP CompetitiveN
      FormWhite lyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₆₁H₁₁₃N₂₁O₁₆
      Chemical formulaC₆₁H₁₁₃N₂₁O₁₆
      Hygroscopic Hygroscopic
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Target(Hsp25) kinase
      Primary Target K<sub>i</sub>8.1 µM against (Hsp25) kinase
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceH-Lys-Lys-Lys-Ala-Leu-Asn-Arg-Gln-Leu-Gly-Val-Ala-Ala-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for up to months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      385880-1MG 04055977190311

      Documentation

      Hsp25 Kinase Inhibitor - Calbiochem MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      Hsp25 Kinase Inhibitor - Calbiochem Certificati d'Analisi

      TitoloNumero di lotto
      385880

      Riferimenti bibliografici

      Panoramica delle referenze
      Katsoulidis, E., et al. 2005. Cancer Res. 65, 9029.
      Hayess, K., and Benndorf, R. 1997. Biochem. Pharmacol. 53, 1239.
      Scheda tecnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-March-2009 JSW
      SynonymsMK2 Inhibitor, KKKALNRQLGVAA, MAPKAP Kinase-2 Inhibitor
      DescriptionA 13-residue, cell-permeable peptide that acts as a potent and selective inhibitor of mammalian heat-shock protein (Hsp25) kinase. Inhibits Hsp25 kinase competitively with respect to the substrate peptide (Ki = 8.1 µM) and non-competitive with respect to ATP (Ki = 134 µM). [Hsp 25 kinase is also called mitogen-activated protein kinase-activated protein kinase-2 (MK2).]
      FormWhite lyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₆₁H₁₁₃N₂₁O₁₆
      Peptide SequenceH-Lys-Lys-Lys-Ala-Leu-Asn-Arg-Gln-Leu-Gly-Val-Ala-Ala-OH
      Purity≥98% by HPLC
      SolubilityDMSO or H₂O
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing recosntitution, aliquot and freeze (-20°C). Stock solutions are stable for up to months at -20°C.
      Toxicity Standard Handling
      ReferencesKatsoulidis, E., et al. 2005. Cancer Res. 65, 9029.
      Hayess, K., and Benndorf, R. 1997. Biochem. Pharmacol. 53, 1239.