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345731 GDF-5, Mouse, Recombinant

345731
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Panoramica

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Purity
≥95% by SDS-PAGE

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345731-50UG
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      Description
      OverviewRecombinant, mouse growth differentiation factor 5 (GDF-5) consisting of amino acids 376-495, expressed in E. coli with and without an N-terminal methionine. GDF-5, a member of the bone morphogenetic protein family, is involved in regulation of myogenesis, bone morphogenesis, neuron differentiation and survival, and chondrogenesis regulation.
      Catalogue Number345731
      Brand Family Calbiochem®
      SynonymsCartilage-derived morphogenetic protein 1 (CDMP-1)
      References
      ReferencesSettle, S.H., Jr., et al. 2003. Dev. Biol. 254, 116.
      Massague, J., et al. 2000. Genes and Dev. 14, 627.
      FrancisWest, P.H., et al. 1999.
      Development 126, 1035. Inada, M., et al. 1996. BBRC 222, 317.
      Nishitoh, H., et al. 1996. J. Biol. Chem. 271, 21345.
      Storm, E.E., et al. 1994. Nature 368, 639.
      Product Information
      FormSolid
      FormulationLyophilized from 0.2 µm filter-sterilized Acetonitrile, TFA, BSA.
      Quality LevelMQ100
      Applications
      ApplicationGDF-5, Mouse, Recombinant, consists of amino acids 376-495 and is expressed in E. coli with and without an N-terminal methionine. Involved in myogenesis, bone morphogenesis & neuron differentiation.
      Biological Information
      Biological activityED₅₀ = 1-4 µg/ml as measured by induction of alkaline phosphatase production by ATDC5 mouse chondrogenic cells. (Nakamura, K. et al. 1999. Exp. Cell Res. 250, 351.)
      Purity≥95% by SDS-PAGE
      Physicochemical Information
      ContaminantsEndotoxin: <1.0 EU/µg protein
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
      Global Trade Item Number
      Numero di catalogo GTIN
      345731-50UG 04055977193817