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14-487M Cdk3/Cyclin E Protein, active, 250 µg

Active complex of recombinant full length human Cdk3 containing a C-terminal His6-tag & recombinant full-length human Cyclin E containing an N-terminal GST-tag, for use in Kinase Assays.

Cdk3/Cyclin E Protein, active, 250 µg: MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.
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14-487M
250 µg  Also available in 10 μg size (cat#14-487) and in bulk (cat# 14-487-K).
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      Replacement Information
      Description
      Catalogue Number14-487M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionCdk3/Cyclin E Protein, active, 250 µg
      OverviewComplex of recombinant full length human cdk3 containing a C-terminal His6-tag, and recombinant full-length human cyclin E containing an N-terminal GST-tag
      References
      Product Information
      Quality LevelMQ300
      Applications
      ApplicationActive complex of recombinant full length human Cdk3 containing a C-terminal His6-tag & recombinant full-length human Cyclin E containing an N-terminal GST-tag, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      SourceBoth are expressed by baculovirus in Sf21 insect cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0.
      Gene Symbol
      • CDK3
      Protein TargetCDK3/cyclinE
      Purification MethodNi-NTA agarose
      Target Sub-FamilyCMGC
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: Q00526 # Probably involved in the control of the cell cycle. Interacts with a yet unknown type of cyclin. Can phosphorylate histone H1.
      SIZE: 305 amino acids; 35046 Da
      SUBUNIT: Interacts with CABLES1 (By similarity).
      SIMILARITY: SwissProt: Q00526 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. & Contains 1 protein kinase domain.
      Molecular Weight36kDa (cdk3), 74kDa (cyclin E)
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by phosphorylation of Histone H1
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions1 year at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-487) and in bulk (cat# 14-487-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      14-487M 04053252269479

      Prodotti e applicazioni correlate

      Alternative Packsize

      Numero di catalogo Descrizione  
      14-487 Cdk3/Cyclin E Protein, active, 10 µg Prezzi e disponibilità

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      Categorie

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases