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189513 Autotaxin Inhibitor IV, HA155 - CAS 1312201-00-5 - Calbiochem

The Autotaxin Inhibitor IV, HA155 controls the biological activity of Autotaxin. This small molecule/inhibitor is primarily used for Cell Structure applications.

MSDS (material safety data sheet) o SDS, certificato d’analisi (CoA) e certificato di qualità (CoQ), dossier, brochure e altri documenti disponibili.

Sinonimi: Atx Inhibitor IV, HA155, (Z)-4-((4-((3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden)-methyl)phenoxy)methyl)benzeneboronic acid

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189513
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Tabella delle specifiche principali

CAS #Empirical Formula
1312201-00-5C₂₄H₁₉BFNO₅S

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189513-10MG
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      Description
      OverviewA ~5-fold more potent (IC50 = 5.7 nM) para-isomer boronate analog of Autotaxin Inhibitor II, HA130 (Cat. No. 189511) that efficiently blocks thrombin-stimulated lysophosphatidic acid secretion in platelets and in mammalian cells.
      Catalogue Number189513
      Brand Family Calbiochem®
      SynonymsAtx Inhibitor IV, HA155, (Z)-4-((4-((3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden)-methyl)phenoxy)methyl)benzeneboronic acid
      References
      ReferencesFulkerson, Z., et al. 2011. J. Biol. Chem. 286, 34654.
      Hausmann, J., et al. 2011. Nat. Struct. Mol. Biol. 18, 198.
      Albers, H.M.H.G., et al. 2011. J. Med. Chem. 54, 4619.
      Albers, H.M.H.G., et al. 2010. J. Med. Chem. 53, 4958.
      Product Information
      CAS number1312201-00-5
      FormYellow powder
      Hill FormulaC₂₄H₁₉BFNO₅S
      Chemical formulaC₂₄H₁₉BFNO₅S
      Hygroscopic Hygroscopic
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Numero di catalogo GTIN
      189513-10MG 04055977221893

      Documentation

      Autotaxin Inhibitor IV, HA155 - CAS 1312201-00-5 - Calbiochem MSDS

      Titolo

      Scheda di sicurezza (MSDS) 

      Riferimenti bibliografici

      Panoramica delle referenze
      Fulkerson, Z., et al. 2011. J. Biol. Chem. 286, 34654.
      Hausmann, J., et al. 2011. Nat. Struct. Mol. Biol. 18, 198.
      Albers, H.M.H.G., et al. 2011. J. Med. Chem. 54, 4619.
      Albers, H.M.H.G., et al. 2010. J. Med. Chem. 53, 4958.
      Scheda tecnica

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision30-November-2012 JSW
      SynonymsAtx Inhibitor IV, HA155, (Z)-4-((4-((3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan-5-yliden)-methyl)phenoxy)methyl)benzeneboronic acid
      DescriptionA ~5-fold more potent (IC50 = 5.7 nM) para-isomer boronate analog of Autotaxin Inhibitor II, HA130 (Cat. No. 189511) that efficiently blocks thrombin-stimulated lysophosphatidic acid secretion in platelets and in mammalian cells.
      FormYellow powder
      Intert gas (Yes/No) Packaged under inert gas
      CAS number1312201-00-5
      Chemical formulaC₂₄H₁₉BFNO₅S
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityDMSO (100 mg/ml)
      Storage Protect from light
      -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesFulkerson, Z., et al. 2011. J. Biol. Chem. 286, 34654.
      Hausmann, J., et al. 2011. Nat. Struct. Mol. Biol. 18, 198.
      Albers, H.M.H.G., et al. 2011. J. Med. Chem. 54, 4619.
      Albers, H.M.H.G., et al. 2010. J. Med. Chem. 53, 4958.